ISSN |
1948-5190 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Case Report |
Article Title |
Cronkhite-Canada syndrome: First case report from Egypt and North Africa
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Ahmed Elsayed Alzamzamy, Ashraf Aboubakr, Hussein H Okasha, Abeer Abdellatef, Shaimaa Elkholy, Mahmoudd Wahba, Mohamed Alboraie, Hussein Elsayed and Mohamed O Othman |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Ahmed Elsayed Alzamzamy, MD, PhD, Consultant Physician-Scientist, Senior Lecturer, Department of Gastroenterology and Hepatology, Maadi Armed Forces Medical Complex, Military Medical Academy, Maadi Kornich El Nile, Cairo 11711, Egypt. dr_zamzamy@hotmail.com |
Key Words |
Gastrointestinal polyposis; Thickened gastric mucosa; Cronkhite-Canada syndrome; Case report |
Core Tip |
Cronkhite-Canada syndrome (CCS) is a rare acquired polyposis with unknown aetiology. To date about 500 cases have been reported worldwide, we reported an Egyptian patient of CCS. Most of CCS were reported from Japan, and for our knowledge, our case is the 1st case reported from Egypt and North Africa. Cases presented with gastrointestinal (GI) polyposis and marked thickened gastric mucosa and folds represent challenging cases and diagnostic dilemmas. The diagnosis was based on history, physical examination, endoscopic findings, and the histology. CCS is typically characterized by GI symptoms, such as diarrhea and skin changes (e.g., alopecia, pigmentation, and nail dystrophy), while endoscopic features include diffuse polyps throughout the entire GIT, except for the esophagus. Pathological types of polyps in CCS mainly include inflammatory, hyperplastic, hamartomatous, and/or adenomatous polyps. CCS can be complicated by many diseases and has a malignant tendency with a high mortality rate. There is no uniform standard treatment for CCS. |
Publish Date |
2022-10-12 07:58 |
Citation |
Alzamzamy AE, Aboubakr A, Okasha HH, Abdellatef A, Elkholy S, Wahba M, Alboraie M, Elsayed H, Othman MO. Cronkhite-Canada syndrome: First case report from Egypt and North Africa. World J Gastrointest Endosc 2022; 14(10): 642-647 |
URL |
https://www.wjgnet.com/1948-5190/full/v14/i10/642.htm |
DOI |
https://dx.doi.org/10.4253/wjge.v14.i10.642 |