Publication Name	World Journal of Gastroenterology
Manuscript ID	7815
Country	China

Received	2013-12-01 09:23
Peer-Review Started	2013-12-02 09:44
To Make the First Decision	2014-02-14 12:45
Return for Revision	2014-02-20 13:57
Revised	2014-03-27 09:37
Second Decision	2014-04-23 09:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-23 10:15
Articles in Press	2014-05-23 09:24
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-21 08:07
Typeset the Manuscript	2014-06-27 19:13
Publish the Manuscript Online	2014-07-14 17:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Prospective Study
Article Title	APE1 polymorphisms are associated with colorectal cancer susceptibility in Chinese Hans
Manuscript Source	Invited Manuscript
All Author List	Shi-Heng Zhang, Lin-Ang Wang, Zheng Li, Yu Peng, Yan-Ping Cun, Nan Dai, Yi Cheng, He Xiao, Yan-Li Xiong and Dong Wang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81171904 National Natural Science Foundation of China 81001000
Corresponding Author	Dong Wang, MD, PhD, Cancer Center, Daping Hospital and Research Institution of Surgery, Third Military Medical University, No. 10 Changjiang Zhi Rd, Yuzhong District, Chongqing 400042, China. dongwang64@hotmail.com
Key Words	Apurinic endonuclease 1; Base excision repair; Single nucleotide polymorphisms; Colorectal cancer; X-ray repair cross-complementing groups
Core Tip	There are discrepancies in reports concerning the association between polymorphisms in genes involved in the base excision DNA repair pathway (OGG1, APE1, and XRCC1) and colorectal cancer susceptibility. This study examines four of these polymorphisms in a Chinese Han population from the southwest region of China. Results show that the APE1 148 Glu/Glu genotype is associated with an increased risk of CRC. Moreover, analyses examining gene-behavior interactions revealed that smoking may influence the relationship between the XRCC1 Arg399Gln polymorphism and CRC risk.
Publish Date	2014-07-14 17:39
Citation	Zhang SH, Wang LA, Li Z, Peng Y, Cun YP, Dai N, Cheng Y, Xiao H, Xiong YL, Wang D. APE1 polymorphisms are associated with colorectal cancer susceptibility in Chinese Hans. World J Gastroenterol 2014; 20(26): 8700-8708
URL	http://www.wjgnet.com/1007-9327/full/v20/i26/8700.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i26.8700

Full Article (PDF)	WJG-20-8700.pdf
Full Article (Word)	WJG-20-8700.doc
Manuscript File	7815-Review.docx
Answering Reviewers	7815-Answering reviewers.pdf
Copyright License Agreement	7815-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7815-Language certificate.pdf
Peer-review Report	7815-Peer reviews.pdf
Scientific Editor Work List	7815-Scientific editor work list.doc