Publication Name	World Journal of Biological Chemistry
Manuscript ID	7862
Country	United States

Received	2013-12-04 08:15
Peer-Review Started	2013-12-04 18:28
To Make the First Decision	2014-02-13 16:28
Return for Revision	2014-02-20 20:00
Revised	2014-02-27 04:16
Second Decision	2014-04-29 08:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-29 08:44
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-19 12:09
Publish the Manuscript Online	2014-06-11 10:30

ISSN	1949-8454 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Review
Article Title	Regulation of cell survival and death during Flavivirus infections
Manuscript Source	Invited Manuscript
All Author List	Sounak Ghosh Roy, Beata Sadigh, Emmanuel Datan, Richard A Lockshin and Zahra Zakeri
Funding Agency and Grant Number
Corresponding Author	Zahra Zakeri, PhD, Department of Biology, Queens College and Graduate Center of the City University of New York, 65-30 Kissena Blvd, Queens, New York, NY 11367, United States. zahra_zakeri@hotmail.com
Key Words	Flavivirus; Dengue virus; West Nile virus; Japanese encephalitis virus; Programmed cell death; Apoptosis; Extrinsic pathway; Intrinsic pathway; Autophagy; Necrosis
Core Tip	The pathogenicity of Flaviviruses derives from their ability to infect many types of cells. They can activate both intrinsic and extrinsic pathways of apoptosis, by many means. Dengue and Japanese encephalitis virus can also activate autophagy, whereby autophagy temporarily spares the infected cell, allowing longer reproduction of virus and protecting the cell against other stresses. Given the versatility of these viruses, we need to understand much better how the specific viral proteins affect the pathways to apoptosis and autophagy. Only in this manner will we be able to minimize the pathology that they cause.
Publish Date	2014-06-11 10:30
Citation	Ghosh Roy S, Sadigh B, Datan E, Lockshin RA, Zakeri Z. Regulation of cell survival and death during Flavivirus infections. World J Biol Chem 2014; 5(2): 93-105
URL	http://www.wjgnet.com/1949-8454/full/v5/i2/93.htm
DOI	http://dx.doi.org/10.4331/wjbc.v5.i2.93

Full Article (PDF)	wjbc-5-93.pdf
Full Article (Word)	wjbc-5-93.doc
Manuscript File	7862-Review.docx
Answering Reviewers	7862- Answering reviewers.pdf
Copyright License Agreement	7862-Copyright assignment.pdf
Peer-review Report	7862-Peer reviewer(s).pdf
Scientific Editor Work List	7862-Scientific editor work list.doc