| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Prospective Study |
| Article Title |
Real-time in vivo distal margin selection using confocal laser endomicroscopy in transanal total mesorectal excision for rectal cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jie Tan, Hong-Li Ji, Yao-Wen Hu, Zhi-Ming Li, Bao-Xiong Zhuang, Hai-Jun Deng, Ya-Nan Wang, Ji-Xiang Zheng, Wei Jiang and Jun Yan |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82273360 |
| Science and Technology Planning Project of Guangzhou City |
202206010085 |
| Clinical Research Project of Southern Medical University |
LC2016PY010 |
| Clinical Research Project of Nanfang Hospital |
2018CR034 |
|
| Corresponding Author |
Jun Yan, MD, PhD, Chief Doctor, Professor, Surgeon, Department of General Surgery, Nanfang Hospital, No. 1838 North Guangzhou Road, Guangzhou 510515, Guangdong Province, China. yanjunfudan@163.com |
| Key Words |
Transanal total mesorectal excision; Probe-based confocal laser endomicroscopy; Optical biopsy; Distal resection margin; Low rectal cancer |
| Core Tip |
Transanal total mesorectal excision (TaTME) allows patients even with ultra-low rectal cancer to be treated with sphincter-saving surgery. However, low rectal cancer resection with sphincter preservation may lead to a positive distal resection margin (DRM), with a high risk for local recurrence. Confocal laser endomicroscopy (CLE) enables the real-time, in vivo optical biopsy of living tissue. Real-time in vivo probe-based CLE examination can provide optical biopsy and is feasible and safe for selecting the DRM during TaTME for low rectal cancer. |
| Publish Date |
2022-12-27 09:49 |
| Citation |
Tan J, Ji HL, Hu YW, Li ZM, Zhuang BX, Deng HJ, Wang YN, Zheng JX, Jiang W, Yan J. Real-time in vivo distal margin selection using confocal laser endomicroscopy in transanal total mesorectal excision for rectal cancer. World J Gastrointest Surg 2022; 14(12): 1375-1386 |
| URL |
https://www.wjgnet.com/1948-9366/full/v14/i12/1375.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v14.i12.1375 |
