Publication Name	World Journal of Gastroenterology
Manuscript ID	79050
Country	China

Received	2022-08-01 14:50
Peer-Review Started	2022-08-01 14:53
To Make the First Decision
Return for Revision	2022-08-19 06:30
Revised	2022-08-31 13:17
Second Decision	2022-09-23 03:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-09-23 16:01
Articles in Press	2022-09-23 16:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-09-30 06:07
Publish the Manuscript Online	2022-10-12 04:24

ISSN	1007-9327 (print) and 2219-2840 (online)
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Category	Microbiology
Manuscript Type	Minireviews
Article Title	Oxidative stress bridges the gut microbiota and the occurrence of frailty syndrome
Manuscript Source	Invited Manuscript
All Author List	Si-Yue Chen, Tong-Yao Wang, Chao Zhao and Hui-Jing Wang
ORCID	Author(s) ORCID Number Tong-Yao Wang http://orcid.org/0000-0002-8998-5509 Chao Zhao http://orcid.org/0000-0001-7349-306X Hui-Jing Wang http://orcid.org/0000-0002-4246-233X
Funding Agency and Grant Number	Funding Agency Grant Number National Key Research and Development Program of China 2018YFC2002000, 2018YFC2000500/03 Shanghai Natural Science Foundation 21ZR1409200
Corresponding Author	Hui-Jing Wang, PhD, Associate Professor, Laboratory of Neuropsychopharmacology, College of Fundamental Medicine, Shanghai University of Medicine & Health Science, No. 279, Zhouzhu Highway, Pudong New Area, Shanghai 201318, China. wanghj@sumhs.edu.cn
Key Words	Oxidative stress; Gut microbiota; Frail syndrome; Traditional Chinese medicine
Core Tip	Frailty is defined as a decrease in the reserve and restoring capacity of the body. It is recognized that oxidative stress (OS) is involved in frailty in multiple ways; however, the underlying mechanisms are still unknown. The association between the gut microbiota (GM) and frailty was recently reported. Herein, we propose that OS is involved in the association between the GM and the occurrence of frailty syndrome. The role of the imbalance between OS and dysbiosis is discussed in this review.
Publish Date	2022-10-12 04:24
Citation	Chen SY, Wang TY, Zhao C, Wang HJ. Oxidative stress bridges the gut microbiota and the occurrence of frailty syndrome. World J Gastroenterol 2022; 28(38): 5547-5556
URL	https://www.wjgnet.com/1007-9327/full/v28/i38/5547.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i38.5547

Full Article (PDF)	WJG-28-5547.pdf
Full Article (Word)	WJG-28-5547.docx
Manuscript File	79050_Auto_Edited-LM.docx
Answering Reviewers	79050-Answering reviewers.pdf
Audio Core Tip	79050-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	79050-Conflict-of-interest statement.pdf
Copyright License Agreement	79050-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	79050-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	79050-Language certificate.pdf
Peer-review Report	79050-Peer-review(s).pdf
Scientific Misconduct Check	79050-Bing-Wang JJ-2.png
Scientific Editor Work List	79050-Scientific editor work list.pdf
CrossCheck Report	79050-CrossCheck report.pdf