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Articles Published Processes
2/6/2023 6:38:44 AM | Browse: 212 | Download: 548
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Received |
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2022-09-19 16:40 |
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Peer-Review Started |
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2022-09-19 16:42 |
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To Make the First Decision |
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Return for Revision |
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2022-12-13 02:47 |
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Revised |
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2022-12-22 11:43 |
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Second Decision |
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2023-01-09 03:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-01-09 09:15 |
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Articles in Press |
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2023-01-09 09:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-01-06 04:56 |
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Typeset the Manuscript |
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2023-01-10 10:03 |
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Publish the Manuscript Online |
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2023-02-06 06:38 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Case Report |
| Article Title |
Pneumocystis jirovecii diagnosed by next-generation sequencing of bronchoscopic alveolar lavage fluid: A case report and review of literature
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Qing-Wei Cheng, Hong-Li Shen, Zhi-Hui Dong, Qian-Qian Zhang, Ya-Fen Wang, Jin Yan, Yu-Sheng Wang and Ning-Gang Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ning-Gang Zhang, MD, Associate Chief Physician, Department of Gastrointestinal Oncology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, No. 3 Zhigong Xincun Street, Xinhualing District, Taiyuan 030013, Shanxi Province, China. zng1120@163.com |
| Key Words |
Renal cell carcinoma; Everolimus; Pneumocystis jirovecii pneumonia; Next-generation sequencing; Bronchoscopic alveolar lavage fluid; Case report |
| Core Tip |
The application of molecular targeted agents and immune checkpoint inhibitors have greatly improved the prognosis of advanced renal cell carcinoma (RCC). We report a patient with advanced RCC treated with multiple lines of molecular targeted agents, who developed a Pneumocystis jirovecii pneumonia after treatment with everolimus in combination with lenvatinib. The pathogenic organism was identified by next-generation sequencing (NGS) of bronchoscopic alveolar lavage fluid (BALF) and successfully treated with trimethoprim-sulfamethoxazole. Evaluating BALF with NGS technology might be used to detect pathogens and determine the correct treatment plan for patients with rare infections caused by the use of molecular targeted agents. |
| Publish Date |
2023-02-06 06:38 |
| Citation |
Cheng QW, Shen HL, Dong ZH, Zhang QQ, Wang YF, Yan J, Wang YS, Zhang NG. Pneumocystis jirovecii diagnosed by next-generation sequencing of bronchoscopic alveolar lavage fluid: A case report and review of literature. World J Clin Cases 2023; 11(4): 866-873 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i4/866.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i4.866 |
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