Publication Name	World Journal of Clinical Cases
Manuscript ID	79431
Country	China

Received	2022-08-20 17:37
Peer-Review Started	2022-08-20 17:38
To Make the First Decision
Return for Revision	2022-10-12 01:57
Revised	2022-10-25 16:23
Second Decision	2022-11-02 03:13
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-11-02 07:43
Articles in Press	2022-11-02 07:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-11-06 01:27
Publish the Manuscript Online	2022-11-23 09:44

ISSN	2307-8960 (online)
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Category	Clinical Neurology
Manuscript Type	Case Report
Article Title	Typical imaging manifestation of neuronal intranuclear inclusion disease in a man with unsteady gait: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Xue Gao, Zhi-Ding Shao and Lei Zhu
ORCID	Author(s) ORCID Number Xue Gao http://orcid.org/0000-0002-7187-2688 Lei Zhu http://orcid.org/0000-0003-1299-3655
Funding Agency and Grant Number
Corresponding Author	Xue Gao, MM, Doctor, Doctor, Department of Neurology , The second affiliated hospital of Wannan Medical College, Kangfu Road, Wuhu 241000, Anhui Province, China. 1159760747@qq.com
Key Words	Gait; Neuronal intranuclear inclusion disease; Magnetic resonance imaging; Biopsy; Genetics; Case report
Core Tip	Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative disease that has gradually gained recognition in recent years. We report a patient with typical NIID imaging findings of high signal intensity along the corticomedullary junction on magnetic resonance imaging. The main symptoms of NIID in older adults are a progressive course of cognitive impairment and unsteady walking. Gene testing indicated that GGC repeats were slightly expanded in the NOTCH2NLC gene. NIID was therefore suspected. Unfortunately, he refused a skin biopsy. Currently, the patient is being followed-up regularly in our outpatient clinic. We will continue to monitor the evolution of this patient.
Publish Date	2022-11-23 09:44
Citation	Gao X, Shao ZD, Zhu L. Typical imaging manifestation of neuronal intranuclear inclusion disease in a man with unsteady gait: A case report. World J Clin Cases 2022; 10(33): 12388-12394
URL	https://www.wjgnet.com/2307-8960/full/v10/i33/12388.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i33.12388

Full Article (PDF)	WJCC-10-12388.pdf
Full Article (Word)	WJCC-10-12388.docx
Manuscript File	79431_Auto_Edited-LJH-JLW.docx
Answering Reviewers	79431-Answering reviewers.pdf
Audio Core Tip	79431-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	79431-Conflict-of-interest statement.pdf
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Signed Consent for Treatment Form(s) or Document(s)	79431-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	79431-Language certificate.pdf
Peer-review Report	79431-Peer-review(s).pdf
Scientific Misconduct Check	79431-Bing-Liu JH-2.jpg
Scientific Misconduct Check	79431-CrossCheck.jpg
Scientific Editor Work List	79431-Scientific editor work list.pdf
CrossCheck Report	79431-CrossCheck report.pdf