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Articles Published Processes
12/27/2022 10:06:45 AM | Browse: 482 | Download: 1372
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Received |
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2022-09-05 18:01 |
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Peer-Review Started |
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2022-09-05 18:03 |
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First Decision by Editorial Office Director |
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2022-11-05 07:36 |
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Return for Revision |
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2022-11-05 07:36 |
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Revised |
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2022-11-07 20:05 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2022-11-25 03:06 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2022-11-27 17:24 |
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Articles in Press |
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2022-11-27 17:24 |
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Edit the Manuscript by Language Editor |
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2022-12-04 22:46 |
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Typeset the Manuscript |
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2022-12-20 14:44 |
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Publish the Manuscript Online |
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2022-12-27 10:06 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Minireviews |
| Article Title |
Molecular mechanisms implicated in SARS-CoV-2 liver tropism
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jorge Quarleri and M. Victoria Delpino |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
M. Victoria Delpino, PhD, Adjunct Professor, Senior Researcher, Institute for Biomedical Research on Retroviruses and AIDS, Faculty of Medical Sciences, National Scientific and Technical Research Council-University of Buenos Aires, Paraguay 2155 Piso 11, Buenos Aires 1121, Argentina. mdelpino@ffyb.uba.ar |
| Key Words |
SARS-CoV-2; Viral hepatitis; Non-infectious liver disease; Hyperinflammation |
| Core Tip |
Clinical manifestations of coronavirus disease-2019 (COVID-19) may be triggered by the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the liver. SARS-CoV-2 genomic RNA and its replicative intermediates were found in liver tissues. SARS-CoV-2 causes direct cholangiocyte damage. Systemic inflammation due to COVID-19 correlated with the degree of acute liver injury as revealed by the rise in aspartate aminotransferase levels. SARS-CoV-2 infection increased the risk of morbidity and mortality in patients with a history of advanced liver disease. |
| Publish Date |
2022-12-27 10:06 |
| Citation |
Quarleri J, Delpino MV. Molecular mechanisms implicated in SARS-CoV-2 liver tropism. World J Gastroenterol 2022; 28(48): 6875-6887 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i48/6875.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i48.6875 |
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