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Articles Published Processes
1/18/2023 3:45:51 AM | Browse: 309 | Download: 735
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Received |
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2022-09-08 15:11 |
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Peer-Review Started |
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2022-09-08 15:13 |
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To Make the First Decision |
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Return for Revision |
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2022-09-19 12:23 |
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Revised |
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2022-10-03 09:23 |
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Second Decision |
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2022-11-18 04:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-11-22 02:56 |
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Articles in Press |
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2022-11-22 02:56 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-11-13 21:00 |
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Typeset the Manuscript |
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2023-01-12 03:26 |
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Publish the Manuscript Online |
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2023-01-18 03:45 |
ISSN |
2220-3249 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Minireviews |
Article Title |
Association between COVID-19 and chronic liver disease: Mechanism, diagnosis, damage, and treatment
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Manuscript Source |
Invited Manuscript |
All Author List |
Ruo-Bing Qi and Zheng-Hao Wu |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Zheng-Hao Wu, MD, Doctor, Doctor, Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 13, Hanghang Road, Qiaokou District, Wuhan 430000, Hubei Province, China. wu_zhenghao@126.com |
Key Words |
SARS-CoV-2; COVID-19; Chronic liver disease; Angiotensin-converting enzyme 2; Hepatotoxicity; Calcineurin inhibitors |
Core Tip |
In this review, we discussed the hepatotropic nature of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and described the distribution of receptors for SARS-CoV-2 in the vascular endothelium and cholangiocytes of the liver. We proposed mechanisms for possible viral entry that mediate liver injury, such as liver fibrosis. Due to SARS-CoV-2-induced liver damage, many coronavirus disease 2019 (COVID-19) patients develop liver dysfunction. We discussed the longer disease duration and higher mortality following SARS-CoV-2 infection in chronic liver disease patients. Correspondingly, relevant risk factors and possible mechanisms were proposed. Finally, we discussed the potential hepatotoxicity of COVID-19-related vaccines and drugs. |
Publish Date |
2023-01-18 03:45 |
Citation |
Qi RB, Wu ZH. Association between COVID-19 and chronic liver disease: Mechanism, diagnosis, damage, and treatment. World J Virol 2023; 12(1): 22-29 |
URL |
https://www.wjgnet.com/2220-3249/full/v12/i1/22.htm |
DOI |
https://dx.doi.org/10.5501/wjv.v12.i1.22 |
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