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1/18/2023 3:45:51 AM | Browse: 173 | Download: 316
Publication Name World Journal of Virology
Manuscript ID 79823
Country China
Received
2022-09-08 15:11
Peer-Review Started
2022-09-08 15:13
To Make the First Decision
Return for Revision
2022-09-19 12:23
Revised
2022-10-03 09:23
Second Decision
2022-11-18 04:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-11-22 02:56
Articles in Press
2022-11-22 02:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-11-13 21:00
Typeset the Manuscript
2023-01-12 03:26
Publish the Manuscript Online
2023-01-18 03:45
ISSN 2220-3249 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Association between COVID-19 and chronic liver disease: Mechanism, diagnosis, damage, and treatment
Manuscript Source Invited Manuscript
All Author List Ruo-Bing Qi and Zheng-Hao Wu
ORCID
Author(s) ORCID Number
Ruo-Bing Qi http://orcid.org/0000-0002-4471-2726
Zheng-Hao Wu http://orcid.org/0000-0001-8468-1234
Funding Agency and Grant Number
Corresponding Author Zheng-Hao Wu, MD, Doctor, Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 13, Hanghang Road, Qiaokou District, Wuhan 430000, Hubei Province, China. wu_zhenghao@126.com
Key Words SARS-CoV-2; COVID-19; Chronic liver disease; Angiotensin-converting enzyme 2; Hepatotoxicity; Calcineurin inhibitors
Core Tip In this review, we discussed the hepatotropic nature of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and described the distribution of receptors for SARS-CoV-2 in the vascular endothelium and cholangiocytes of the liver. We proposed mechanisms for possible viral entry that mediate liver injury, such as liver fibrosis. Due to SARS-CoV-2-induced liver damage, many coronavirus disease 2019 (COVID-19) patients develop liver dysfunction. We discussed the longer disease duration and higher mortality following SARS-CoV-2 infection in chronic liver disease patients. Correspondingly, relevant risk factors and possible mechanisms were proposed. Finally, we discussed the potential hepatotoxicity of COVID-19-related vaccines and drugs.
Publish Date 2023-01-18 03:45
Citation Qi RB, Wu ZH. Association between COVID-19 and chronic liver disease: Mechanism, diagnosis, damage, and treatment. World J Virol 2023; 12(1): 22-29
URL https://www.wjgnet.com/2220-3249/full/v12/i1/22.htm
DOI https://dx.doi.org/10.5501/wjv.v12.i1.22
Full Article (PDF) WJV-12-22.pdf
Full Article (Word) WJV-12-22.docx
Manuscript File 79823_Auto_Edited-LM.docx
Answering Reviewers 79823-Answering reviewers.pdf
Audio Core Tip 79823-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 79823-Conflict-of-interest statement.pdf
Copyright License Agreement 79823-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 79823-Language certificate.pdf
Peer-review Report 79823-Peer-review(s).pdf
Scientific Misconduct Check 79823-Bing-Wang JJ-2.png
Scientific Editor Work List 79823-Scientific editor work list.pdf