Publication Name	World Journal of Diabetes
Manuscript ID	80041
Country	China

Received	2022-09-14 21:24
Peer-Review Started	2022-09-14 21:26
To Make the First Decision
Return for Revision	2022-10-05 06:40
Revised	2022-10-22 06:07
Second Decision	2022-10-31 03:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-10-31 22:14
Articles in Press	2022-10-31 22:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-11-07 02:18
Publish the Manuscript Online	2022-11-11 10:05

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Engineering, Biomedical
Manuscript Type	Minireviews
Article Title	Role of defensins in diabetic wound healing
Manuscript Source	Invited Manuscript
All Author List	Zhi-Xiang Tan, Rui Tao, Si-Cheng Li, Bing-Zheng Shen, Lan-Xia Meng and Zhan-Yong Zhu
ORCID	Author(s) ORCID Number Zhi-Xiang Tan http://orcid.org/0000-0002-1614-133X Rui Tao http://orcid.org/0000-0001-8782-4421 Si-Cheng Li http://orcid.org/0000-0003-4354-0288 Bing-Zheng Shen http://orcid.org/0000-0003-1205-0139 Lan-Xia Meng http://orcid.org/0000-0001-5307-671X Zhan-Yong Zhu http://orcid.org/0000-0003-4323-4862
Funding Agency and Grant Number	Funding Agency Grant Number Scientific Research Project of Hubei Health Committee No. WJ2021F106
Corresponding Author	Zhan-Yong Zhu, MD, PhD, Associate Chief Physician, Doctor, Doctor, Surgeon, Department of Plastic Surgery, Renmin Hospital of Wuhan University, No. 238 Jiefang Road, Wuhan 430060, Hubei Province, China. zyzhu@whu.edu.cn
Key Words	Defensin; Diabetic wound; Wound healing; Inflammation; Re- epithelialization; Tissue regeneration
Core Tip	Although previous studies have suggested that defensins have a function in the promotion of wound healing, their mechanism is still unclear. In this review, we discuss the potential role of various defensins in refractory diabetic wounds and their properties, including immunoregulation, promotion of re-epithelialization, collagen deposition, vascular regeneration, and neurological recovery, as well as antimicrobial activity.
Publish Date	2022-11-11 10:05
Citation	Tan ZX, Tao R, Li SC, Shen BZ, Meng LX, Zhu ZY. Role of defensins in diabetic wound healing. World J Diabetes 2022; 13(11): 962-971
URL	https://www.wjgnet.com/1948-9358/full/v13/i11/962.htm
DOI	https://dx.doi.org/10.4239/wjd.v13.i11.962

Full Article (PDF)	WJD-13-962.pdf
Full Article (Word)	WJD-13-962.docx
Manuscript File	80041_Auto_Edited-LM.docx
Answering Reviewers	80041-Answering reviewers.pdf
Audio Core Tip	80041-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	80041-Conflict-of-interest statement.pdf
Copyright License Agreement	80041-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	80041-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	80041-Language certificate.pdf
Scientific Misconduct Check	80041-Bing-Chen YL-2.png
Scientific Editor Work List	80041-Scientific editor work list.pdf
CrossCheck Report	80041-CrossCheck report.pdf
CrossCheck Report	80041-Peer-review(s).pdf