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Articles Published Processes
1/10/2023 8:58:44 AM | Browse: 216 | Download: 613
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Received |
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2022-10-10 04:38 |
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Peer-Review Started |
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2022-10-03 00:55 |
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To Make the First Decision |
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Return for Revision |
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2022-11-18 07:27 |
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Revised |
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2022-11-22 01:26 |
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Second Decision |
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2022-12-20 08:13 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-12-21 07:58 |
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Articles in Press |
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2022-12-21 07:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-01-05 13:09 |
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Publish the Manuscript Online |
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2023-01-10 08:58 |
ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Immunology |
Manuscript Type |
Minireviews |
Article Title |
Future applications of exosomes delivering resolvins and cytokines in facilitating diabetic foot ulcer healing
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Manuscript Source |
Invited Manuscript |
All Author List |
Joshua P B Littig, Rebecca Moellmer, Devendra K Agrawal and Vikrant Rai |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Western University of Health Sciences, Pomona, California |
IMR Rai 12397B |
National Institutes of Health, United States |
R01 HL144125, R01 HL147662 |
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Corresponding Author |
Vikrant Rai, MBBS, PhD, Assistant Professor, Translational Research, Western University of Health Sciences, 309 E Second Street, Pomona, CA 91766, United States. vrai@westernu.edu |
Key Words |
Diabetic foot ulcer; Chronic inflammation; Amputation; Exosomes; Cytokines; Resolvins |
Core Tip |
Nonhealing diabetic foot ulcers (DFUs) are a debilitating condition with the risk of amputation despite the advanced treatment strategies. Chronic inflammation, decreased granulation tissue formation, and decreased angiogenesis underlies the pathogenesis of nonhealing. Targeted delivery of therapeutics targeting immune cell infiltration and chronic inflammation with loaded exosomes may increase the efficacy of treatment. We herein discuss the potential of exosomes loaded with resolvins and drugs targeting inflammatory cytokines to promote DFUs healing. |
Publish Date |
2023-01-10 08:58 |
Citation |
<p>Littig JPB, Moellmer R, Agrawal DK, Rai V. Future applications of exosomes delivering resolvins and cytokines in facilitating diabetic foot ulcer healing. <i>World J Diabetes</i> 2024; In press</p> |
URL |
https://www.wjgnet.com/1948-9358/full/v14/i1/35.htm |
DOI |
https://dx.doi.org/10.4239/wjd.v14.i1.35 |
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