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Articles Published Processes
2/21/2023 6:19:16 AM | Browse: 352 | Download: 639
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Received |
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2022-10-21 20:13 |
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Peer-Review Started |
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2022-10-21 20:16 |
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To Make the First Decision |
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Return for Revision |
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2022-11-30 08:17 |
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Revised |
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2022-12-16 17:52 |
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Second Decision |
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2023-02-07 04:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-02-14 19:30 |
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Articles in Press |
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2023-02-14 19:30 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-02-15 06:24 |
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Publish the Manuscript Online |
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2023-02-21 06:19 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Mucosal healing and inflammatory bowel disease: Therapeutic implications and new targets
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Megan Lynn Otte, Raju Lama Tamang, Julia Papapanagiotou, Rizwan Ahmad, Punita Dhawan and Amar B Singh |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| NIH |
DK124095 |
| NCI |
CA250383 |
| Veterans Administration |
BX002761 |
| Veterans Administration |
BX002086 |
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| Corresponding Author |
Amar B Singh, PhD, Professor, Deaprtment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68118, United States. amar.singh@unmc.edu |
| Key Words |
Inflammation; Injury/repair; Mucosal healing; Mucosal barrier; Therapeutics; Colitis |
| Core Tip |
Mucosal healing (MH) is vital in maintaining intestinal homeostasis and protecting against infection and injury. MH has emerged as an important clinical criterion in effective treatment of inflammatory bowel disease (IBD). However, there remains a relative lack of therapeutics that can restore MH due to the complexity of the disease and healing processes. Through increased understanding of the molecular mechanisms of MH, tissue damage from IBD may be ameliorated by developing novel therapeutics. Here, we introduce the concept of MH and its relevance in IBD, and discuss the mechanisms of IBD and potential strategies for altering these processes for inducing MH |
| Publish Date |
2023-02-21 06:19 |
| Citation |
Otte ML, Lama Tamang R, Papapanagiotou J, Ahmad R, Dhawan P, Singh AB. Mucosal healing and inflammatory bowel disease: Therapeutic implications and new targets. World J Gastroenterol 2023; 29(7): 1157-1172 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i7/1157.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i7.1157 |
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