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2/21/2023 6:19:16 AM | Browse: 204 | Download: 328
Publication Name World Journal of Gastroenterology
Manuscript ID 81028
Country United States
Received
2022-10-21 20:13
Peer-Review Started
2022-10-21 20:16
To Make the First Decision
Return for Revision
2022-11-30 08:17
Revised
2022-12-16 17:52
Second Decision
2023-02-07 04:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-02-14 19:30
Articles in Press
2023-02-14 19:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-02-15 06:24
Publish the Manuscript Online
2023-02-21 06:19
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Mucosal healing and inflammatory bowel disease: Therapeutic implications and new targets
Manuscript Source Invited Manuscript
All Author List Megan Lynn Otte, Raju Lama Tamang, Julia Papapanagiotou, Rizwan Ahmad, Punita Dhawan and Amar B Singh
ORCID
Author(s) ORCID Number
Megan Lynn Otte http://orcid.org/0000-0003-2984-8198
Rizwan Ahmad http://orcid.org/0000-0003-0331-6687
Punita Dhawan http://orcid.org/0000-0003-3434-8155
Amar B Singh http://orcid.org/0000-0003-1908-8594
Funding Agency and Grant Number
Funding Agency Grant Number
NIH DK124095
NCI CA250383
Veterans Administration BX002761
Veterans Administration BX002086
Corresponding Author Amar B Singh, PhD, Professor, Deaprtment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68118, United States. amar.singh@unmc.edu
Key Words Inflammation; Injury/repair; Mucosal healing; Mucosal barrier; Therapeutics; Colitis
Core Tip Mucosal healing (MH) is vital in maintaining intestinal homeostasis and protecting against infection and injury. MH has emerged as an important clinical criterion in effective treatment of inflammatory bowel disease (IBD). However, there remains a relative lack of therapeutics that can restore MH due to the complexity of the disease and healing processes. Through increased understanding of the molecular mechanisms of MH, tissue damage from IBD may be ameliorated by developing novel therapeutics. Here, we introduce the concept of MH and its relevance in IBD, and discuss the mechanisms of IBD and potential strategies for altering these processes for inducing MH
Publish Date 2023-02-21 06:19
Citation Otte ML, Lama Tamang R, Papapanagiotou J, Ahmad R, Dhawan P, Singh AB. Mucosal healing and inflammatory bowel disease: Therapeutic implications and new targets. World J Gastroenterol 2023; 29(7): 1157-1172
URL https://www.wjgnet.com/1007-9327/full/v29/i7/1157.htm
DOI https://dx.doi.org/10.3748/wjg.v29.i7.1157
Full Article (PDF) WJG-29-1157.pdf
Full Article (Word) WJG-29-1157.docx
Manuscript File 81028_Auto_Edited-LM.docx
Answering Reviewers 81028-Answering reviewers.pdf
Audio Core Tip 81028-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 81028-Conflict-of-interest statement.pdf
Copyright License Agreement 81028-Copyright license agreement.pdf
Peer-review Report 81028-Peer-review(s).pdf
Scientific Misconduct Check 81028-Bing-Liu GL-2.png
Scientific Editor Work List 81028-Scientific editor work list.pdf