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Articles Published Processes
1/3/2023 10:13:58 AM | Browse: 222 | Download: 750
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Received |
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2022-11-07 15:45 |
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Peer-Review Started |
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2022-11-07 15:47 |
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To Make the First Decision |
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Return for Revision |
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2022-11-25 03:14 |
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Revised |
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2022-11-30 18:33 |
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Second Decision |
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2022-12-22 03:22 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-12-23 02:51 |
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Articles in Press |
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2022-12-23 02:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-12-26 00:09 |
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Publish the Manuscript Online |
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2023-01-03 10:13 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Observational Study |
| Article Title |
Role of cerebrospinal fluid lactate in diagnosing meningitis in critically ill patients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Devraj Yadav, Omender Singh, Deven Juneja, Amit Goel, Sahil Kataria and Anisha Beniwal |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Deven Juneja, Visiting Professor, FCCP, MBBS, Director, Director, Institute of Critical Care Medicine, Max Super Speciality Hospital, Saket, 1, Press Enclave Road, New Delhi 110017, India. devenjuneja@gmail.com |
| Key Words |
Encephalitis; Cerebrospinal fluid; Critically ill; CSF lactates; Meningitis |
| Core Tip |
We conducted a prospective, observational cohort study to assess the efficacy of cerebrospinal fluid (CSF) lactate in diagnosing meningitis in critically ill patients. 71 patients were included and 23 were diagnosed with meningitis. There was a significant correlation of CSF lactate levels with CSF cultures and meningo-encephalitis panel. CSF lactate (> 2.72 mmol/L) showed good accuracy in diagnosing meningitis with an area under the curve (AUC) of 0.81, sensitivity 82.6%, and specificity 72.9%. These values were comparable to those of CSF total leucocyte count (TLC) and protein. Twelve patients with bacterial meningitis had significantly higher CSF lactate (8.9 ± 4.7 mmol/L) than those with non-bacterial meningitis (4.2 ± 3.8 mmol/L), P = 0.006. To conclude, CSF lactate may be used to aid in our diagnosis of meningitis in critically ill patients. |
| Publish Date |
2023-01-03 10:13 |
| Citation |
Yadav D, Singh O, Juneja D, Goel A, Kataria S, Beniwal A. Role of cerebrospinal fluid lactate in diagnosing meningitis in critically ill patients. World J Crit Care Med 2023; 12(1): 1-9 |
| URL |
https://www.wjgnet.com/2220-3141/full/v12/i1/1.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v12.i1.1 |
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