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8/8/2014 5:10:00 PM | Browse: 1138 | Download: 938
Publication Name World Journal of Diabetes
Manuscript ID 8136
Country/Territory United States
Received
2013-12-18 09:01
Peer-Review Started
2013-12-18 16:00
To Make the First Decision
2014-02-27 11:28
Return for Revision
2014-03-05 09:22
Revised
2014-03-24 01:24
Second Decision
2014-06-03 16:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-06-03 16:42
Articles in Press
2014-06-03 16:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-08-05 18:39
Publish the Manuscript Online
2014-08-08 17:11
ISSN 1948-9358 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Topic Highlights
Article Title Benefits of healthy adipose tissue in the treatment of diabetes
Manuscript Source Invited Manuscript
All Author List Subhadra C Gunawardana
Funding Agency and Grant Number
Corresponding Author Subhadra C Gunawardana, PhD, Research Assistant Professor, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, United States. subhadra.gunawardana@vanderbilt.edu
Key Words Adipose tissue; Diabetes; Insulin-independent; Transplantation; Subcutaneous; Adipokines; Metabolic disease
Core Tip Diabetes mellitus is characterized by perturbation of glucose homeostasis due to insulin deficiency, either absolute or relative. Traditional treatments over the past century have focused on insulin replacement and/or enhancing insulin sensitivity. Ultimate goal in treating diabetes is to re-establish glucose regulation. Recent studies increasingly show the ability of extra-pancreatic hormones, particularly of adipose tissue origin, to compensate for insulin. Adipose tissue is a versatile endocrine organ which, under appropriate circumstances, can exert numerous metabolic benefits and may maintain glucose regulation entirely independent of endocrine pancreas. This review discusses such alternative therapies based on beneficial effects of healthy adipose tissue.
Publish Date 2014-08-08 17:11
Citation Gunawardana SC. Benefits of healthy adipose tissue in the treatment of diabetes. World J Diabetes 2014; 5(4): 420-430
URL http://www.wjgnet.com/1948-9358/full/v5/i4/420.htm
DOI http://dx.doi.org/10.4239/wjd.v5.i4.420
Full Article (PDF) WJD-5-420.pdf
Full Article (Word) WJD-5-420.doc
Manuscript File 8136-Review.docx
Answering Reviewers 8136-Answering reviewers.pdf
Copyright License Agreement 8136-Copyright assignment.pdf
Peer-review Report 8136-Peer review(s).pdf
Scientific Misconduct Check 8136-CrossCheck.jpg
Scientific Editor Work List 8136-Scientific editor work list.pdf