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Articles Published Processes
8/8/2014 5:10:00 PM | Browse: 1285 | Download: 1191
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Received |
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2013-12-18 09:01 |
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Peer-Review Started |
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2013-12-18 16:00 |
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To Make the First Decision |
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2014-02-27 11:28 |
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Return for Revision |
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2014-03-05 09:22 |
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Revised |
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2014-03-24 01:24 |
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Second Decision |
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2014-06-03 16:24 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-06-03 16:42 |
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Articles in Press |
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2014-06-03 16:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-08-05 18:39 |
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Publish the Manuscript Online |
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2014-08-08 17:11 |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Topic Highlights |
| Article Title |
Benefits of healthy adipose tissue in the treatment of diabetes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Subhadra C Gunawardana |
| Funding Agency and Grant Number |
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| Corresponding Author |
Subhadra C Gunawardana, PhD, Research Assistant Professor, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, United States. subhadra.gunawardana@vanderbilt.edu |
| Key Words |
Adipose tissue; Diabetes; Insulin-independent; Transplantation; Subcutaneous; Adipokines; Metabolic disease |
| Core Tip |
Diabetes mellitus is characterized by perturbation of glucose homeostasis due to insulin deficiency, either absolute or relative. Traditional treatments over the past century have focused on insulin replacement and/or enhancing insulin sensitivity. Ultimate goal in treating diabetes is to re-establish glucose regulation. Recent studies increasingly show the ability of extra-pancreatic hormones, particularly of adipose tissue origin, to compensate for insulin. Adipose tissue is a versatile endocrine organ which, under appropriate circumstances, can exert numerous metabolic benefits and may maintain glucose regulation entirely independent of endocrine pancreas. This review discusses such alternative therapies based on beneficial effects of healthy adipose tissue. |
| Publish Date |
2014-08-08 17:11 |
| Citation |
Gunawardana SC. Benefits of healthy adipose tissue in the treatment of diabetes. World J Diabetes 2014; 5(4): 420-430 |
| URL |
http://www.wjgnet.com/1948-9358/full/v5/i4/420.htm |
| DOI |
http://dx.doi.org/10.4239/wjd.v5.i4.420 |
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