Publication Name	World Journal of Diabetes
Manuscript ID	8136
Country	United States

Received	2013-12-18 09:01
Peer-Review Started	2013-12-18 16:00
First Decision by Editorial Office Director
Return for Revision	2014-03-05 09:22
Revised	2014-03-24 01:24
Publication Fee Transferred
Second Decision by Editor	2014-06-03 16:24
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-06-03 16:42
Articles in Press	2014-06-03 16:42
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-05 18:39
Publish the Manuscript Online	2014-08-08 17:11

ISSN	1948-9358 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Topic Highlights
Article Title	Benefits of healthy adipose tissue in the treatment of diabetes
Manuscript Source	Invited Manuscript
All Author List	Subhadra C Gunawardana
Funding Agency and Grant Number
Corresponding Author	Subhadra C Gunawardana, PhD, Research Assistant Professor, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, United States. subhadra.gunawardana@vanderbilt.edu
Key Words	Adipose tissue; Diabetes; Insulin-independent; Transplantation; Subcutaneous; Adipokines; Metabolic disease
Core Tip	Diabetes mellitus is characterized by perturbation of glucose homeostasis due to insulin deficiency, either absolute or relative. Traditional treatments over the past century have focused on insulin replacement and/or enhancing insulin sensitivity. Ultimate goal in treating diabetes is to re-establish glucose regulation. Recent studies increasingly show the ability of extra-pancreatic hormones, particularly of adipose tissue origin, to compensate for insulin. Adipose tissue is a versatile endocrine organ which, under appropriate circumstances, can exert numerous metabolic benefits and may maintain glucose regulation entirely independent of endocrine pancreas. This review discusses such alternative therapies based on beneficial effects of healthy adipose tissue.
Publish Date	2014-08-08 17:11
Citation	Gunawardana SC. Benefits of healthy adipose tissue in the treatment of diabetes. World J Diabetes 2014; 5(4): 420-430
URL	http://www.wjgnet.com/1948-9358/full/v5/i4/420.htm
DOI	http://dx.doi.org/10.4239/wjd.v5.i4.420

Full Article (PDF)	WJD-5-420.pdf
Full Article (Word)	WJD-5-420.doc
Manuscript File	8136-Review.docx
Answering Reviewers	8136-Answering reviewers.pdf
Copyright License Agreement	8136-Copyright assignment.pdf
Peer-review Report	8136-Peer review(s).pdf
Scientific Misconduct Check	8136-CrossCheck.jpg
Scientific Editor Work List	8136-Scientific editor work list.pdf