Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	8147
Country	Germany

Received	2013-12-18 11:01
Peer-Review Started	2013-12-19 09:21
To Make the First Decision	2014-01-08 14:54
Return for Revision	2014-01-21 15:01
Revised	2014-01-24 19:39
Second Decision	2014-03-17 14:33
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-17 14:45
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-21 17:59
Typeset the Manuscript	2014-05-19 07:54
Publish the Manuscript Online	2014-05-20 17:09

ISSN	2150-5330 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Immunology
Manuscript Type	Minireviews
Article Title	Role of gamma-delta T cells in liver inflammation and fibrosis
Manuscript Source	Invited Manuscript
All Author List	Linda Hammerich and Frank Tacke
Funding Agency and Grant Number	Funding Agency Grant Number German Research Foundation DFG Ta434/2-1 German Research Foundation SFB/TRR57 Interdisciplinary Center for Clinical Research (IZKF) Aachen
Corresponding Author	Frank Tacke, MD, PhD, Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstraße 30, 52074 Aachen, Germany. frank.tacke@gmx.net
Key Words	Liver fibrosis; Liver cirrhosis; Interleukin-17; Gamma/delta T cells; Cytokines
Core Tip	The liver is particularly enriched in unconventional T cells expressing the gamma-delta T cell receptor and the functional role of these gamma-delta (??) T cells in liver diseases is being intensively investigated at present. ?? T cells accumulate in inflamed liver and their function appears highly dependent on the distinct subsets. In principle, ???T cells can be protective as well as pathogenic in the context of liver inflammation. This review summarizes the current knowledge of ?? T cell effector functions and the cytokines produced by these cells in human liver diseases and murine experimental models of acute and chronic liver injury.
Publish Date	2014-05-20 17:09
Citation	Hammerich L, Tacke F. Role of gamma-delta T cells in liver inflammation and fibrosis. World J Gastrointest Pathophysiol 2014; 5(2): 107-113
URL	http://www.wjgnet.com/2150-5330/full/v5/i2/107.htm
DOI	http://dx.doi.org/10.4291/wjgp.v5.i2.107

Full Article (PDF)	WJGP-5-107.pdf
Full Article (Word)	WJGP-5-107.doc
Manuscript File	8147-Review.docx
Answering Reviewers	8147-Answering reviewers.pdf
Copyright License Agreement	8147-Copyright assignment.pdf
Peer-review Report	8147-Peer reviewer(s).pdf
Scientific Editor Work List	8147-Scientific editor work list.doc