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Articles Published Processes
3/15/2023 3:41:16 PM | Browse: 125 | Download: 202
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Received |
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2022-11-15 21:00 |
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Peer-Review Started |
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2022-11-15 21:03 |
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To Make the First Decision |
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Return for Revision |
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2022-12-26 08:31 |
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Revised |
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2023-01-13 19:21 |
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Second Decision |
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2023-02-22 04:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2023-02-23 04:42 |
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Articles in Press |
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2023-02-23 04:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-02-16 02:09 |
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Typeset the Manuscript |
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2023-03-09 10:36 |
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Publish the Manuscript Online |
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2023-03-15 15:41 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Minireviews |
| Article Title |
AT1 receptor downregulation: A mechanism for improving glucose homeostasis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Diana L Lopez, Oscar E Casillas, Hiram J Jaramillo, Tatiana Romero-Garcia and J. Gustavo Vazquez-Jimenez |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
J. Gustavo Vazquez-Jimenez, MD, PhD, Doctor, Research Scientist, School of Medicine, Autonomous University of Baja California, Centro Cívico, Mexicali 21000, Baja California, Mexico. gustavo.vazquez@uabc.edu.mx |
| Key Words |
Type 2 diabetes mellitus; High blood pressure; Insulin receptor; Insulin signaling pathway; AT1 receptor; Angiotensin II signaling pathway |
| Core Tip |
Type 2 diabetes mellitus (T2DM) is one of the most prevalent diseases in the world, whose chronic lack of control is associated with the development of several manifestations that can incapacitate the patient. Recently, it has been described that the prescription of antihypertensive drugs in the presence of proteinuria in diabetic patients can prevent kidney failure, and notably, antihypertensive drugs can also be coadjuvant to improve glucose homeostasis. In this review, we disclose the pathophysiological mechanism in which hypertension is related to the development of insulin resistance, contrasting it with the results obtained during clinical practice, giving a new approach to the use of antihypertensive drugs that beyond avoiding kidney damage, are coadjuvant in the treatment of T2DM. |
| Publish Date |
2023-03-15 15:41 |
| Citation |
Lopez DL, Casillas OE, Jaramillo HJ, Romero-Garcia T, Vazquez-Jimenez JG. AT1 receptor downregulation: A mechanism for improving glucose homeostasis. World J Diabetes 2023; 14(3): 170-178 |
| URL |
https://www.wjgnet.com/1948-9358/full/v14/i3/170.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v14.i3.170 |
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