| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Hematologic diseases: High risk of Clostridium difficile associated diarrhea
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Tae-Geun Gweon, Myung-Gyu Choi, Myong Ki Baeg, Chul-Hyun Lim, Jae Myung Park, In Seok Lee, Sang Woo Kim, Dong-Gun Lee, Yeon Joon Park and Jong Wook Lee |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ministry of Education, Science and Technology, Seoul, South Korea |
NRF-2011-0031644 |
|
| Corresponding Author |
Myung-Gyu Choi, MD, PhD, Division of Gastroenterology, Department of Internal Medicine, Seoul St Mary’s hospital, The Catholic University of Korea, College of Medicine, Banpodaero 222 Seocho-Gu, Seoul, 137-701, South Korea. choim@catholic.ac.kr |
| Key Words |
Clostridium difficile associated diarrhea; Incidence; Clinical outcome; Patients with hematologic disease; Intravenous immunoglobulin |
| Core Tip |
Our study included a large number of Clostridium difficile associated diarrhea (CDAD) patients at a dedicated hematopoietic stem cell transplantation center, which is one of the most renown centers for the treatment of hematologic diseases. The incidence and recurrence of CDAD was higher in patients with hematologic disease than in those with nonhematologic disease. This might be related to higher use of antibiotics. Use of intravenous immunoglobulin was associated with a lower CDAD recurrence rate. Based on our data, we suggest that physicians should be more aware of the higher incidence and rate of recurrence of CDAD in patients with hematologic disease. |
| Publish Date |
2014-06-06 16:55 |
| Citation |
Gweon TG, Choi MG, Baeg MK, Lim CH, Park JM, Lee IS, Kim SW, Lee DG, Park YJ, Lee JW. Hematologic diseases: High risk of Clostridium difficile associated diarrhea. World J Gastroenterol 2014; 20(21): 6602-6607 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i21/6602.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i21.6602 |
