Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	82027
Country	China

Received	2022-12-04 14:34
Peer-Review Started	2022-12-04 14:35
To Make the First Decision
Return for Revision	2022-12-26 03:18
Revised	2023-01-09 08:46
Second Decision	2023-03-08 03:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-03-08 18:07
Articles in Press	2023-03-08 18:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-04-06 04:39
Publish the Manuscript Online	2023-04-12 08:10

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Review
Article Title	Lipid metabolism of hepatocellular carcinoma impacts targeted therapy and immunotherapy
Manuscript Source	Invited Manuscript
All Author List	Xiao-Chen Feng, Fu-Chen Liu, Wu-Yu Chen, Jin Du and Hui Liu
ORCID	Author(s) ORCID Number Hui Liu http://orcid.org/0000-0003-4599-5702
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81970453 National Natural Science Foundation of China 82270634 Shanghai Science and Technology Innovation Action Plan Project 20XD1405100
Corresponding Author	Hui Liu, MD, PhD, Chief Doctor, Professor, The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, No. 225 Changhai Road, Shanghai 200082, China. liuhuigg@hotmail.com
Key Words	Hepatocellular carcinoma; Lipid metabolism; Targeted therapy; Immunotherapy; Drug resistance; Therapeutic efficacy
Core Tip	This review systematically summarizes the aberrant changes of lipid metabolism in hepatocellular carcinoma (HCC), and for the first time expounds the impact of lipid metabolism on HCC targeted therapy and immunotherapy. It vividly displayed the changes of lipid metabolism in HCC and the targets of some reagents by drawing figures, and summarized the impact of lipid metabolism related reagents on HCC targeted therapy and immunotherapy through table.
Publish Date	2023-04-12 08:10
Citation	Feng XC, Liu FC, Chen WY, Du J, Liu H. Lipid metabolism of hepatocellular carcinoma impacts targeted therapy and immunotherapy. World J Gastrointest Oncol 2023; 15(4): 617-631
URL	https://www.wjgnet.com/1948-5204/full/v15/i4/617.htm
DOI	https://dx.doi.org/10.4251/wjgo.v15.i4.617

Full Article (PDF)	WJGO-15-617.pdf
Full Article (Word)	WJGO-15-617.docx
Manuscript File	82027_Auto_Edited-LM.docx
Answering Reviewers	82027-Answering reviewers.pdf
Audio Core Tip	82027-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	82027-Conflict-of-interest statement.pdf
Copyright License Agreement	82027-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	82027-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	82027-Language certificate.pdf
Peer-review Report	82027-Peer-review(s).pdf
Scientific Misconduct Check	82027-Bing-Fan JR-2.png
Scientific Editor Work List	82027-Scientific editor work list.pdf