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Articles Published Processes
5/15/2023 3:23:22 PM | Browse: 204 | Download: 504
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Received |
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2022-12-30 15:51 |
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Peer-Review Started |
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2022-12-07 12:56 |
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To Make the First Decision |
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Return for Revision |
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2023-02-28 09:26 |
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Revised |
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2023-03-10 09:59 |
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Second Decision |
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2023-04-12 03:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-12 07:38 |
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Articles in Press |
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2023-04-12 07:38 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-05-09 01:46 |
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Publish the Manuscript Online |
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2023-05-15 15:23 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Review |
| Article Title |
Early diabetic kidney disease: Focus on the glycocalyx
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hui Yu, Yi-Yun Song and Xian-Hua Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Shandong Province of China |
ZR2019MH072 |
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| Corresponding Author |
Xian-Hua Li, MD, Professor, Department of Nephrology, Qilu Hospital of Shandong University, No. 107 Wenhua Xi Road, Jinan 250012, Shandong Province, China. lixianhua7075@sina.com |
| Key Words |
Glycocalyx; Diabetic kidney disease; Endothelial cells; Reactive oxygen species; Microalbuminuria; Enzyme |
| Core Tip |
In the diabetic microenvironment, various harmful factors, such as oxidative stress and inflammation, contribute to endothelial glycocalyx (EG) disruption through direct damage to the glycocalyx or indirect degradation due to the upregulation of related sheddases. Shedding one or more components after damage to the EG is an early sign of numerous pathological states, including diabetes. The loss of filtration barrier integrity can lead to microalbuminuria, which is predictive of diabetic kidney disease (DKD). Identifying and targeting the key molecules involved in glycocalyx damage thus represent current hot topics in DKD research. |
| Publish Date |
2023-05-15 15:23 |
| Citation |
Yu H, Song YY, Li XH. Early diabetic kidney disease: Focus on the glycocalyx. World J Diabetes 2023; 14(5): 460-480 |
| URL |
https://www.wjgnet.com/1948-9358/full/v14/i5/460.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v14.i5.460 |
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