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8/22/2014 5:28:00 PM | Browse: 437 | Download: 335
Publication Name World Journal of Clinical Oncology
Manuscript ID 8263
Country of Manuscript Source Italy
Received
2013-12-22 15:21
Peer-Review Started
2013-12-22 18:54
To Make the First Decision
2014-02-27 11:20
Return for Revision
2014-03-06 09:21
Revised
2014-04-24 19:32
Second Decision
2014-05-29 09:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-05-29 09:52
Articles in Press
2014-05-29 10:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-07-18 10:13
Publish the Manuscript Online
2014-08-01 15:17
ISSN 2218-4333 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Topic Highlights
Article Title Molecular pathogenesis of bone metastases in breast cancer: Proven and emerging therapeutic targets
Manuscript Source Invited Manuscript
All Author List Nadia Rucci, Patrizia Sanità, Simona Delle Monache, Edoardo Alesse and Adriano Angelucci
Funding Agency and Grant Number
Corresponding author Adriano Angelucci, Professor, Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, Via Vetoio, Coppito 67100, L’Aquila, Italy. adriano.angelucci@univaq.it
Keywords Breast cancer; Bone metastasis; Targeted therapy; Osteoclasts
Core Tip Breast cancer cells preferentially colonize bone sites during their metastatic diffusion. Bone microenvironment and tumor cells operate a reciprocal selective pressure that results in the formation of osteolytic lesion and tumor progression. Targeting the molecular factors involved in this interaction has been demonstrated to be an effective strategy in preventing the clinical morbidity associated with bone metastases. In this review, we summarize physiopathologic aspects of bone metastases from breast cancer and discuss the most promising therapeutic targets for their future clinical management.
Publish Date 2014-08-01 15:17
Citation Rucci N, Sanità P, Delle Monache S, Alesse E, Angelucci A. Molecular pathogenesis of bone metastases in breast cancer: Proven and emerging therapeutic targets. World J Clin Oncol 2014; 5(3): 335-347
Url http://www.wjgnet.com/2218-4333/full/v5/i3/335.htm
DOI http://dx.doi.org/10.5306/wjco.v5.i3.335
Full Article (PDF) WJCO-5-335.pdf
Full Article (Word) WJCO-5-335.doc
Manuscript File 8263-Review.docx
Answering Reviewers 8263-Answering reviewers.pdf
Copyright License Agreement 8263-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 8263-Language certificate.pdf
Peer-review Report 8263-Peer review(s).pdf
Scientific Misconduct Check 8263-CrossCheck.jpg
Scientific Editor Work List 8263-Scientific editor work list.pdf