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4/24/2023 11:14:10 AM | Browse: 97 | Download: 235
Publication Name World Journal of Gastroenterology
Manuscript ID 82710
Country China
Received
2023-01-09 07:58
Peer-Review Started
2023-01-09 08:00
To Make the First Decision
Return for Revision
2023-02-15 06:38
Revised
2023-02-21 05:36
Second Decision
2023-03-31 03:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-03-31 09:55
Articles in Press
2023-03-31 09:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-04-10 00:43
Publish the Manuscript Online
2023-04-24 11:14
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Predictive value of presepsin and acylcarnitines for severity and biliary drainage in acute cholangitis
Manuscript Source Unsolicited Manuscript
All Author List Han-Yu Zhang, Hong-Li Xiao, Guo-Xing Wang, Zhao-Qing Lu, Miao-Rong Xie and Chun-Sheng Li
ORCID
Author(s) ORCID Number
Han-Yu Zhang http://orcid.org/0000-0002-1865-047X
Hong-Li Xiao http://orcid.org/0000-0002-7353-114X
Guo-Xing Wang http://orcid.org/0000-0003-1379-5749
Zhao-Qing Lu http://orcid.org/0000-0001-8895-1596
Miao-Rong Xie http://orcid.org/0000-0003-2479-9470
Chun-Sheng Li http://orcid.org/0000-0002-3161-4457
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China (General Program) 81773931
Beijing Municipal Administration of Hospitals’ Youth Program QML20170105
Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support ‘‘Yangfan’’ Project ZYLX201804
Corresponding Author Chun-Sheng Li, PhD, Professor, Department of Emergency Medicine, Beijing Friendship Hospital, Capital Medical University, No. 95 Yongan Road, Xicheng District, Beijing 100050, China. lcscyyy@163.com
Key Words Acute cholangitis; Severity; Biliary drainage; Presepsin; Acylcarnitines
Core Tip Acute cholangitis leads to sepsis and organ dysfunction because of biliary obstruction. Identification of predictive biomarkers for patients who require emergent biliary drainage and patients who may progress to systemic bloodstream infection at an early stage of the disease is a key imperative. Our study suggests that presepsin and acetyl-L-carnitine may serve as biomarkers to predict the severity of acute cholangitis and the need for biliary drainage. Innate immune response was associated with mitochondrial metabolic dysfunction.
Publish Date 2023-04-24 11:14
Citation Zhang HY, Xiao HL, Wang GX, Lu ZQ, Xie MR, Li CS. Predictive value of presepsin and acylcarnitines for severity and biliary drainage in acute cholangitis. World J Gastroenterol 2023; 29(16): 2502-2514
URL https://www.wjgnet.com/1007-9327/full/v29/i16/2502.htm
DOI https://dx.doi.org/10.3748/wjg.v29.i16.2502
Full Article (PDF) WJG-29-2502.pdf
Full Article (Word) WJG-29-2502.docx
STROBE Statement 82710-STROBE-Statement-revision.pdf
Manuscript File 82710_Auto_Edited-JLW.docx
Answering Reviewers 82710-Answering reviewers.pdf
Audio Core Tip 82710-Audio core tip.mp3
Biostatistics Review Certificate 82710-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 82710-Conflict-of-interest statement.pdf
Copyright License Agreement 82710-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 82710-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 82710-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 82710-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 82710-Language certificate.pdf
Supplementary Material 82710-Supplementary material.pdf
Peer-review Report 82710-Peer-review(s).pdf
Scientific Misconduct Check 82710-Bing-Yan JP-2.png
Scientific Editor Work List 82710-Scientific editor work list.pdf