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Articles Published Processes
3/7/2023 8:12:13 AM | Browse: 362 | Download: 1100
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Received |
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2023-01-04 05:52 |
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Peer-Review Started |
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2023-01-04 05:55 |
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To Make the First Decision |
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Return for Revision |
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2023-01-14 02:29 |
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Revised |
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2023-01-14 07:55 |
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Second Decision |
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2023-02-21 03:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-02-21 07:32 |
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Articles in Press |
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2023-02-21 07:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-02-24 07:43 |
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Publish the Manuscript Online |
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2023-03-07 08:12 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Pregnancy and medications for inflammatory bowel disease: An updated narrative review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shintaro Akiyama, Joshua M Steinberg, Mariko Kobayashi, Hideo Suzuki and Kiichiro Tsuchiya |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Shintaro Akiyama, MD, MSc, PhD, Lecturer, Department of Gastroenterology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan. akiyama@md.tsukuba.ac.jp |
| Key Words |
Inflammatory bowel disease; Pregnancy; Safety; Biologics; Small molecules |
| Core Tip |
Anti-tumor necrosis factor monotherapy is safe during pregnancy in women with Inflammatory bowel disease (IBD). However, their use in combination with thiopurines may be associated increased risk of neonatal prematurity and infection, although these data are conflicting. According to meta-analyses, vedolizumab and ustekinumab may be associated with early pregnancy loss; however, these data might be biased by IBD activity or small sample sizes. Recent prospective studies have demonstrated these biologics are generally safe during pregnancy. Janus kinase inhibitors are contraindicated during pregnancy as animal studies have demonstrated harmful effects. Calcineurin inhibitors may be considered for pregnant women with IBD who develop clinical relapse. |
| Publish Date |
2023-03-07 08:12 |
| Citation |
Akiyama S, Steinberg JM, Kobayashi M, Suzuki H, Tsuchiya K. Pregnancy and medications for inflammatory bowel disease: An updated narrative review. World J Clin Cases 2023; 11(8): 1730-1740 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i8/1730.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i8.1730 |
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