| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Fecal microbiota transplantation in patients with metabolic syndrome and obesity: A randomized controlled trial
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Alberto Machado da Ponte Neto, Aniele Cristine Ott Clemente, Paula Waki Rosa, Igor Braga Ribeiro, Mateus Pereira Funari, Gabriel Cairo Nunes, Luana Moreira, Luiz Gustavo Sparvoli, Ramon Cortez, Carla Romano Taddei, Márcio C Mancini and Eduardo Guimarães Hourneaux de Moura |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Igor Braga Ribeiro, MD, PhD, Associate Research Scientist, Attending Doctor, Doctor, Doctor, Research Scientist, Departamento de Gastroenterologia, Faculdade de Medicina, Universidade de Sao Paulo, Serviço de Endoscopia Gastrointestinal do Hospital das Clínicas HCFMUSP, Av. Dr Enéas de Carvalho Aguiar, 225, 6o andar, bloco 3, Cerqueira Cesar, São Paulo 05403-010, SP, Brazil. igorbraga1@gmail.com |
| Key Words |
Fecal microbiota transplantation; Metabolic syndrome; Obesity; Endoscopy; Diabetes mellitus; Endocrinology |
| Core Tip |
The prevalence of metabolic syndrome is a pandemic that goes hand in hand with obesity and diabetes, affecting almost half of the world's population. Therapeutic approaches targeting dysbiosis and manipulation of the gut microbiome have become options and are being tested. Such approaches include the use of prebiotics, probiotics, synbiotics, antibiotics and fecal microbiota transplantation (FMT). It is known that FMT can alter the intestinal microbiota and increase its diversity, resulting in a microbiome that can help decrease body fat and increase insulin sensitivity, as well as facilitate the treatment of metabolic syndrome and obesity. This was a randomized controlled trial comparing FMT and a sham procedure in patients with the metabolic syndrome. |
| Publish Date |
2023-06-30 12:54 |
| Citation |
da Ponte Neto AM, Clemente ACO, Rosa PW, Ribeiro IB, Funari MP, Nunes GC, Moreira L, Sparvoli LG, Cortez R, Taddei CR, Mancini MC, de Moura EGH. Fecal microbiota transplantation in patients with metabolic syndrome and obesity: A randomized controlled trial. World J Clin Cases 2023; 11(19): 4612-4624 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i19/4612.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i19.4612 |
