| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Minireviews |
| Article Title |
Machine perfusion and the prevention of ischemic type biliary lesions following liver transplant: What is the evidence?
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Manuel Durán, Rafael Calleja, Angus Hann, George Clarke, Ruben Ciria, Anisa Nutu, Rebeca Sanabria-Mateos, María Dolores Ayllón, Pedro López-Cillero, Hynek Mergental, Javier Briceño and M Thamara P R Perera |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
M Thamara P R Perera, FEBS, FRCS, MBBS, MD, MS, Chairman, Professor, Surgeon, The Liver Unit, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Birmingham B15 2TH, United Kingdom. thamara.perera@uhb.nhs.uk |
| Key Words |
Liver transplant; Ischemic type biliary lesions; Hypothermic oxygenated machine perfusion; Normothermic machine perfusion; Abdominal normothermic regional perfusion; Donation after circulatory death |
| Core Tip |
In recent years, the development of different machine perfusion (MP) strategies has generated interest in their use for both the assessment of grafts and optimization during the preservation period. The different mechanisms behind the diverse array of MP strategies may reduce the extent of cholangiocyte and may have the subsequent clinical effect of preventing the development of ischaemic type biliary lesions (ITBL). This review summarizes the strength and limitations of clinical studies that have been undertaken, their results, and provides a summary of the available literature on MP and the prevention of ITBL. |
| Publish Date |
2023-05-26 08:34 |
| Citation |
Durán M, Calleja R, Hann A, Clarke G, Ciria R, Nutu A, Sanabria-Mateos R, Ayllón MD, López-Cillero P, Mergental H, Briceño J, Perera MTPR. Machine perfusion and the prevention of ischemic type biliary lesions following liver transplant: What is the evidence? World J Gastroenterol 2023; 29(20): 3066-3083 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i20/3066.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i20.3066 |
