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Articles Published Processes
8/25/2014 5:12:00 PM | Browse: 983 | Download: 937
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Received |
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2013-12-26 13:47 |
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Peer-Review Started |
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2013-12-26 15:02 |
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To Make the First Decision |
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Return for Revision |
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Revised |
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2014-02-11 01:53 |
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Second Decision |
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2014-05-14 09:19 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-05-14 09:36 |
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Articles in Press |
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2014-05-23 09:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-07-02 15:25 |
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Publish the Manuscript Online |
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2014-07-21 17:17 |
Category |
Pathology |
Manuscript Type |
Topic Highlights |
Article Title |
Role of liver biopsy in nonalcoholic fatty liver disease
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Manuscript Source |
Invited Manuscript |
All Author List |
ILKe Nalbantoglu and Elizabeth M Brunt |
Funding Agency and Grant Number |
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Corresponding Author |
ILKe Nalbantoglu, MD, Department of Pathology and Immunology, Washington University School of Medicine, Campus Box 8118, 660 S Euclid Ave, Saint Louis, MO 63110, United States. inalbantoglu@path.wustl.edu |
Key Words |
Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Liver biopsy; Histopathology; Grading and staging |
Core Tip |
Nonalcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease; no clinical or serologic tests have yet replaced liver biopsy for definitive diagnosis. The histologic spectrum includes steatosis, steatohepatitis, and cirrhosis with or without active steatohepatitis. Hepatocellular carcinoma may occur in cirrhosis, or prior to cirrhosis. Liver biopsy provides vital data for patient care, clinical trials, and for ongoing research into nuances of the disease process. The histologic spectrum of NAFLD, features with co-existent diseases, differential diagnoses, grading and staging methods and the role of liver biopsy, as well as a brief description of non-invasive alternatives, are discussed. |
Publish Date |
2014-07-21 17:17 |
Citation |
Nalbantoglu I, Brunt EM. Role of liver biopsy in nonalcoholic fatty liver disease. World J Gastroenterol 2014; 20(27): 9026-9037 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i27/9026.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i27.9026 |
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