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Articles Published Processes
7/13/2023 8:03:56 AM | Browse: 115 | Download: 302
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Received |
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2023-03-06 07:51 |
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Peer-Review Started |
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2023-03-06 07:51 |
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To Make the First Decision |
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Return for Revision |
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2023-03-14 03:38 |
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Revised |
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2023-03-27 14:13 |
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Second Decision |
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2023-04-27 02:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2023-04-27 06:58 |
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Articles in Press |
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2023-04-27 06:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-07-05 08:24 |
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Publish the Manuscript Online |
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2023-07-13 08:03 |
ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Ophthalmology |
Manuscript Type |
Basic Study |
Article Title |
Analysis of N6-methyladenosine-modified mRNAs in diabetic cataract
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Lei Cai, Xiao-Yan Han, Dan Li, Dong-Mei Ma, Yu-Meng Shi, Yi Lu and Jin Yang |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
No. 82171039 |
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Corresponding Author |
Jin Yang, MD, Chief Physician, Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University, No. 83 Fenyang Road, Shanghai 200031, China. jin_er76@hotmail.com |
Key Words |
N6-methyladenosine; Diabetic cataract; RNA; Ferroptosis; Epitranscriptomic microarray |
Core Tip |
Diabetic cataracts (DCs) are associated with elevated blood sugar levels and usually occur at an earlier age with more rapid progression than age-related cataracts. However, the specific molecular mechanisms underlying DC progression remain to be elucidated. As environmental factors are essential in the pathogenesis of diabetes mellitus, epigenetic changes may be particularly important. Recently, N6-methyladenosine (m6A) has been suggested to play a part in DC progression. The present study elucidated the m6A landscape in DC and simultaneously analyzed the methylation and expression of related mRNA. These analyses indicate that m6A mRNA modifications in lens epithelial cells might be involved in DC progression. |
Publish Date |
2023-07-13 08:03 |
Citation |
Cai L, Han XY, Li D, Ma DM, Shi YM, Lu Y, Yang J. Analysis of N6-methyladenosine-modified mRNAs in diabetic cataract. World J Diabetes 2023; 14(7): 1077-1090 |
URL |
https://www.wjgnet.com/1948-9358/full/v14/i7/1077.htm |
DOI |
https://dx.doi.org/10.4239/wjd.v14.i7.1077 |
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