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Articles Published Processes
5/25/2023 4:10:55 PM | Browse: 197 | Download: 614
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Received |
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2023-02-16 09:03 |
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Peer-Review Started |
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2023-02-16 09:04 |
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To Make the First Decision |
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Return for Revision |
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2023-03-28 07:50 |
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Revised |
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2023-04-07 12:28 |
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Second Decision |
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2023-04-19 02:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-19 07:31 |
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Articles in Press |
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2023-04-19 07:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-05-12 03:50 |
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Publish the Manuscript Online |
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2023-05-25 16:10 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Case Report |
| Article Title |
Co-existing squamous cell carcinoma and chronic myelomonocytic leukemia with ASXL1 and EZH2 gene mutations: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lai-Jun Deng, Yang Dong, Mi-Mi Li and Chang-Gang Sun |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Lai-Jun Deng, MS, Staff Physician, Department of Hematology, Weifang Hospital of Traditional Chinese Medicine, No. 1055 Weizhou Road, Kuiwen District, Weifang 261000, Shandong Province, China. denglaijun1982@163.com |
| Key Words |
Squamous cell carcinoma; Chronic myelomonocytic leukemia; Myeloproliferative neoplasms; Myelodysplastic; ASXL1gene mutations; EZH2 gene mutations; Case report |
| Core Tip |
A 63-year-old male, with a long history of heavy smoking, was diagnosed with chronic myelomonocytic leukemia (CMML), with additional sex combs-like and enhancer of zeste homolog 2 gene mutations, as well as non-small cell lung cancer (squamous cell carcinoma). However, no such mutations were found in the lung cancer tissue. In CMML patients, pulmonary manifestations are non-specific, and the rare presence of malignant tumors in the lungs poses challenges in diagnosis. After receiving azacitidine, programmed cell death protein 1, and platinum-based chemotherapy drugs, the patient developed severe myelosuppression and eventually fatal leukocyte stasis and dyspnea. Therefore, during treatment and observation of CMML, medical practitioners should pay attention to the occurrence and evolution of solid tumors such as lung cancer, and be vigilant of the growth of multiple primary malignant tumors. |
| Publish Date |
2023-05-25 16:10 |
| Citation |
Deng LJ, Dong Y, Li MM, Sun CG. Co-existing squamous cell carcinoma and chronic myelomonocytic leukemia with ASXL1 and EZH2 gene mutations: A case report. World J Clin Cases 2023; 11(15): 3643-3650 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i15/3643.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i15.3643 |
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