| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Emerging role of the gut microbiome in post-infectious irritable bowel syndrome: A literature review
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Vasile Valeriu Lupu, Cristina Mihaela Ghiciuc, Gabriela Stefanescu, Cristina Maria Mihai, Alina Popp, Maria Oana Sasaran, Laura Bozomitu, Iuliana Magdalena Starcea, Anca Adam Raileanu and Ancuta Lupu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Anca Adam Raileanu, MD, PhD, Attending Doctor, Faculty of General Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 16 University Street, Iasi 700115, Romania. anca.adam60@gmail.com |
| Key Words |
Gut microbiome; Infectious gastroenteritis; Irritable bowel syndrome; Post infection syndrome; Pathophysiology; Inflammation |
| Core Tip |
Acute infectious gastroenteritis can trigger the onset of irritable bowel syndrome (IBS), leading to the development of post-infectious IBS (PI-IBS). PI-IBS is a clinical entity associated with gut dysbiosis. Alterations in the gut microbiome can affect the gut–brain axis, visceral sensitivity, intestinal barrier, intestinal secretion, gut motility, and immune activation, which in turn can cause IBS symptoms. A better understanding of PI-IBS is necessary to develop more targeted and effective treatments. Therapies targeting the microbiome, such as probiotics, antibiotics, diet, and fecal microbiota transplants, improve IBS symptoms. There is a lack of evidence of their efficiency in PI-IBS. |
| Publish Date |
2023-06-01 13:04 |
| Citation |
Lupu VV, Ghiciuc CM, Stefanescu G, Mihai CM, Popp A, Sasaran MO, Bozomitu L, Starcea IM, Adam Raileanu A, Lupu A. Emerging role of the gut microbiome in post-infectious irritable bowel syndrome: A literature review. World J Gastroenterol 2023; 29(21): 3241-3256 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i21/3241.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i21.3241 |
