Publication Name	World Journal of Clinical Cases
Manuscript ID	84669
Country	Israel

Received	2023-03-23 16:51
Peer-Review Started	2023-03-23 16:53
To Make the First Decision
Return for Revision	2023-04-20 00:33
Revised	2023-05-17 13:09
Second Decision	2023-06-29 02:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-06-30 03:44
Articles in Press	2023-06-30 03:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-07-14 08:56
Publish the Manuscript Online	2023-07-27 01:26

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Manipulation of the intestinal microbiome-a slow journey to primetime
Manuscript Source	Invited Manuscript
All Author List	Ofra Kriger-Sharabi, Stephen D H Malnick and David Fisher
ORCID	Author(s) ORCID Number Stephen D H Malnick http://orcid.org/0000-0003-1865-8313
Funding Agency and Grant Number
Corresponding Author	Stephen D H Malnick, MD, Doctor, Doctor, Department of Internal Medicine, Kaplan Medical Center, Derech Pasternak 1, Rehovot 76100, Israel. steve_m@clalit.org.il
Key Words	Gut microbiota; Fecal microbiota transplantation; Clostridoides difficile; Metabolic associated fatty liver disease; Irritable bowel syndrome; Inflammatory bowel disease
Core Tip	We review the current literature regarding the microbiome and the pathogenesis and treatment of Clostridoides difficile infection (CDI), metabolic associated fatty liver disease (MAFLD), irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Fecal microbial transplantation is an established treatment option in recurrent CDI. There is also promising evidence of efficacy in MAFLD, IBS and IBD which require further work to establish its role in managing these conditions.
Publish Date	2023-07-27 01:26
Citation	Kriger-Sharabi O, Malnick SDH, Fisher D. Manipulation of the intestinal microbiome-a slow journey to primetime. World J Clin Cases 2023; 11(21): 4975-4988
URL	https://www.wjgnet.com/2307-8960/full/v11/i21/4975.htm
DOI	https://dx.doi.org/10.12998/wjcc.v11.i21.4975

Full Article (PDF)	WJCC-11-4975-with-cover.pdf
Full Article (Word)	WJCC-11-4975.docx
Manuscript File	84669_Auto_Edited-JLW.docx
Answering Reviewers	84669-Answering reviewers.pdf
Audio Core Tip	84669-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	84669-Conflict-of-interest statement.pdf
Copyright License Agreement	84669-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	84669-Language certificate.pdf
Peer-review Report	84669-Peer-review(s).pdf
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Scientific Editor Work List	84669-Scientific editor work list.pdf
CrossCheck Report	84669-CrossCheck report.pdf
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