| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Observational Study |
| Article Title |
Real-world effectiveness and safety of direct-acting antivirals in hepatitis C virus patients with mental disorders
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Dorota Dybowska, Dorota Zarębska-Michaluk, Piotr Rzymski, Hanna Berak, Beata Lorenc, Marek Sitko, Michał Dybowski, Włodzimierz Mazur, Magdalena Tudrujek-Zdunek, Justyna Janocha-Litwin, Ewa Janczewska, Jakub Klapaczyński, Anna Parfieniuk-Kowerda, Anna Piekarska, Barbara Sobala-Szczygieł, Krystyna Dobrowolska, Malgorzata Pawłowska and Robert Flisiak |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Dorota Zarębska-Michaluk, PhD, Assistant Professor, Professor, Department of Infectious Diseases and Allergology, Jan Kochanowski University, Żeromskiego 5, Kielce 25-317, Poland. dorota1010@tlen.pl |
| Key Words |
Hepatitis C; Mental disorders; Direct-acting antivirals |
| Core Tip |
In the population of patients with mental illness, the prevalence of hepatitis C virus infection is many times higher than in the general population. In the era of interferon-based therapy, these patients had minimal access to antiviral treatment due to contraindications to interferon with the risk of exacerbation of psychiatric diseases. Their situation has improved with the introduction of direct-acting antivirals, but data from real-world studies are scarce. This retrospective analysis carried out in the clinical practice confirms the good safety profile and the treatment effectiveness not inferior to that obtained in a population without mental disorders. |
| Publish Date |
2023-06-28 07:41 |
| Citation |
Dybowska D, Zarębska-Michaluk D, Rzymski P, Berak H, Lorenc B, Sitko M, Dybowski M, Mazur W, Tudrujek-Zdunek M, Janocha-Litwin J, Janczewska E, Klapaczyński J, Parfieniuk-Kowerda A, Piekarska A, Sobala-Szczygieł B, Dobrowolska K, Pawłowska M, Flisiak R. Real-world effectiveness and safety of direct-acting antivirals in hepatitis C virus patients with mental disorders. World J Gastroenterol 2023; 29(25): 4085-4098 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i25/4085.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i25.4085 |
