Publication Name	World Journal of Orthopedics
Manuscript ID	85312
Country	Greece

Received	2023-04-22 09:37
Peer-Review Started	2023-04-22 09:41
To Make the First Decision
Return for Revision	2023-05-25 01:59
Revised	2023-06-07 21:39
Second Decision	2023-07-11 02:55
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-07-11 08:39
Articles in Press	2023-07-11 08:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-08-09 06:14
Publish the Manuscript Online	2023-08-17 10:54

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Infectious Diseases
Manuscript Type	Minireviews
Article Title	In vitro laboratory infection research in orthopaedics: Why, when, and how
Manuscript Source	Invited Manuscript
All Author List	Konstantinos Tsikopoulos, Lorenzo Drago, Gabriele Meroni, Dimitrios Kitridis, Byron Chalidis, Fotios Papageorgiou and Paraskevi Papaioannidou
ORCID	Author(s) ORCID Number Konstantinos Tsikopoulos http://orcid.org/0000-0001-5923-4782 Lorenzo Drago http://orcid.org/0000-0002-5206-540X Gabriele Meroni http://orcid.org/0000-0003-2772-6410 Dimitrios Kitridis http://orcid.org/0000-0002-6063-8650 Byron Chalidis http://orcid.org/0000-0003-1305-2734 Fotios Papageorgiou http://orcid.org/0000-0001-6646-9379 Paraskevi Papaioannidou http://orcid.org/0000-0001-8880-0288
Funding Agency and Grant Number
Corresponding Author	Konstantinos Tsikopoulos, PhD, Postdoc, Senior Researcher, 1st Department of Pharmacology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Panepistimioupoli, Thessaloniki 54124, Greece. kostastsikop@gmail.com
Key Words	Biofilm; In vitro; Laboratory research; Methodology
Core Tip	This paper highlights some major orthopaedic research advances at a basic science level. On top of that, it is highlighted that the perception of orthopaedic conditions has fundamentally changed recently, reflecting on clinical practice. We also described the basic aspects of a successful in vitro infection laboratory experiment and expanded on recent evidence relating to molecular biology, ex vivo investigations, and artificial intelligence in orthopaedics.
Publish Date	2023-08-17 10:54
Citation	Tsikopoulos K, Drago L, Meroni G, Kitridis D, Chalidis B, Papageorgiou F, Papaioannidou P. In vitro laboratory infection research in orthopaedics: Why, when, and how. World J Orthop 2023; 14(8): 598-603
URL	https://www.wjgnet.com/2218-5836/full/v14/i8/598.htm
DOI	https://dx.doi.org/10.5312/wjo.v14.i8.598

Full Article (PDF)	WJO-14-598-with-cover.pdf
Full Article (Word)	WJO-14-598.docx
Manuscript File	85312_Auto_Edited-JLW.docx
Answering Reviewers	85312-Answering reviewers.pdf
Audio Core Tip	85312-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	85312-Conflict-of-interest statement.pdf
Copyright License Agreement	85312-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	85312-Language certificate.pdf
Peer-review Report	85312-Peer-review(s).pdf
Scientific Misconduct Check	85312-Bing-Wang JJ-2.png
Scientific Editor Work List	85312-Scientific editor work list.pdf
CrossCheck Report	85312-CrossCheck report.pdf