| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Incidence and prevalence of gastric neuroendocrine tumors in patients with chronic atrophic autoimmune gastritis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Sara Massironi, Camilla Gallo, Alessandra Elvevi, Marta Stegagnini, Lorenzo Andrea Coltro and Pietro Invernizzi |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Sara Massironi, MD, PhD, Chief Physician, Doctor, Doctor, Medical Assistant, Research Scientist, Division of Gastroenterology, Fondazione IRCCS San Gerardo dei Tintori, University of Milano-Bicocca School of Medicine, Via G.B. Pergolesi 33, Monza 20900, Italy. sara.massironi@libero.it |
| Key Words |
Atrophic gastritis; Autoimmune gastritis; Gastrin; Gastric neuroendocrine tumors |
| Core Tip |
Type I gastric neuroendocrine neoplasms (gNENs) in chronic auto-immune gastritis (AIG) are increasingly diagnosed, but no accurate data are available. Moreover, noninvasive biomarkers of gNENs in AIG have been yet identified. According to our results, a non-negligeable annual cumulative gNENs incidence of 5.7% was revealed, and among all considered variables, only gastrin proved to have significantly higher median circulating levels in patients who developed gNENs compared to AIG patients without lesions, nevertheless with a low diagnostic accuracy. Further efforts are needed to identify effective strategies for individualizing endoscopic follow-up of AIG patients, to early diagnose and treat superimposed neuroendocrine lesions. |
| Publish Date |
2023-08-10 14:08 |
| Citation |
Massironi S, Gallo C, Elvevi A, Stegagnini M, Coltro LA, Invernizzi P. Incidence and prevalence of gastric neuroendocrine tumors in patients with chronic atrophic autoimmune gastritis. World J Gastrointest Oncol 2023; 15(8): 1451-1460 |
| URL |
https://www.wjgnet.com/1948-5204/full/v15/i8/1451.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v15.i8.1451 |
