BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
8/22/2014 5:28:00 PM | Browse: 1056 | Download: 1097
 |
Received |
|
2014-01-04 13:33 |
 |
Peer-Review Started |
|
2014-01-04 19:10 |
 |
To Make the First Decision |
|
2014-02-13 16:09 |
 |
Return for Revision |
|
2014-02-19 22:55 |
 |
Revised |
|
2014-03-18 17:54 |
 |
Second Decision |
|
2014-06-27 17:36 |
 |
Accepted by Journal Editor-in-Chief |
|
|
 |
Accepted by Executive Editor-in-Chief |
|
2014-06-27 17:49 |
 |
Articles in Press |
|
2014-06-27 18:10 |
 |
Publication Fee Transferred |
|
|
 |
Edit the Manuscript by Language Editor |
|
|
 |
Typeset the Manuscript |
|
2014-07-21 16:16 |
 |
Publish the Manuscript Online |
|
2014-08-01 15:17 |
Category |
Oncology |
Manuscript Type |
Topic Highlights |
Article Title |
Epithelial-mesenchymal transition transcription factors and miRNAs: “Plastic surgeons” of breast cancer
|
Manuscript Source |
Invited Manuscript |
All Author List |
Caroline Moyret-Lalle, Emmanuelle Ruiz and Alain Puisieux |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Ligue Nationale contre le Cancer |
to Puisieux A |
|
Corresponding Author |
Caroline Moyret-Lalle, PhD, Laboratoire d’EXcellence DEVweCAN, INSERM UMR-S1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, 43 Boulevard du 11 Novembre 1918, 69008 Lyon, France. caroline.moyret-lalle@lyon.unicancer.fr |
Key Words |
Embryonic transcription factors; Epithelial to mesenchymal transition; Breast cancer; MicroRNAs; Dicer; Feedback loop |
Core Tip |
Epithelial-mesenchymal transition (EMT) and the reverse mesenchymal-epithelial transition (MET) are both involved in breast cancer plasticity. Embryonic transcription factors and miRNAs are key players regulating the balance between these two processes allowing cells that underwent EMT to transiently re-acquire epithelial phenotype. Here we highlighted the complex transcription factors/miRNAs regulation networks involved in EMT-MET during breast cancer progression and the central role played by Dicer, the key enzyme of miRNAs processing, in EMT process. These key regulators of EMT-MET may represent predictive markers and potential therapeutic targets for breast cancers. |
Publish Date |
2014-08-01 15:17 |
Citation |
Moyret-Lalle C, Ruiz E, Puisieux A. Epithelial-mesenchymal transition transcription factors and miRNAs: “Plastic surgeons” of breast cancer. World J Clin Oncol 2014; 5(3): 311-322 |
URL |
http://www.wjgnet.com/2218-4333/full/v5/i3/311.htm |
DOI |
http://dx.doi.org/10.5306/wjco.v5.i3.311 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345