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8/26/2014 5:11:00 PM | Browse: 1011 | Download: 1136
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 8746
Country/Territory Japan
Received
2014-01-05 11:47
Peer-Review Started
2014-01-05 14:17
To Make the First Decision
2014-02-27 09:31
Return for Revision
2014-03-06 10:54
Revised
2014-04-02 11:32
Second Decision
2014-05-29 09:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-05-29 09:54
Articles in Press
2014-05-29 10:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-06-10 15:25
Publish the Manuscript Online
2014-06-16 15:27
ISSN 1948-5190 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Autobiography
Article Title Monitoring salivary amylase activity is useful for providing timely analgesia under sedation
Manuscript Source Unsolicited Manuscript
All Author List Masaya Uesato, Yoshihiro Nabeya, Takashi Akai, Masahito Inoue, Yoshiyuki Watanabe, Daisuke Horibe, Hiroshi Kawahira, Hideki Hayashi and Hisahiro Matsubara
Funding Agency and Grant Number
Funding Agency Grant Number
Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science, Japan C: #23591018
Corresponding Author Masaya Uesato, MD, Department of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba 260-8670, Japan. uesato@faculty.chiba-u.jp
Key Words Salivary amylase activity; Endoscopic submucosal dissection; Analgesia; Anesthesia; Sedation; Sympathetic excitement; Gastric wall tension
Core Tip The analgesia in patients during endoscopic submucosal dissection (ESD) under deep sedation (DS) has not yet been developed. There was no way of measuring the degree of the pain in those patients. This study revealed that the salivary amylase activity (sAMY) shown as sympathetic excitement (SE) sometimes was elevated during ESD without any change in circulatory dynamics or consciousness. We suggest that sAMY is elevated when patients feel pain during ESD under DS. By detecting twice the actual sAMY based on the preoperative level, the release of gastric wall tension or the administration of analgesic agents should be considered.
Publish Date 2014-06-16 15:27
Citation Uesato M, Nabeya Y, Akai T, Inoue M, Watanabe Y, Horibe D, Kawahira H, Hayashi H, Matsubara H. Monitoring salivary amylase activity is useful for providing timely analgesia under sedation. World J Gastrointest Endosc 2014; 6(6): 240-247
URL http://www.wjgnet.com/1948-5190/full/v6/i6/240.htm
DOI http://dx.doi.org/10.4253/wjge.v6.i6.240
Full Article (PDF) WJGE-6-240.pdf
Manuscript File 8746-Review.docx
Answering Reviewers 8746-Answering reviewers.pdf
Copyright License Agreement 8746-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 8746-Language certificate.pdf
Peer-review Report 8746-Peer review(s).pdf
Scientific Misconduct Check 8746-CrossCheck.jpg
Scientific Editor Work List 8746-Scientific editor work list.pdf