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10/24/2023 8:39:24 AM | Browse: 142 | Download: 290
Publication Name World Journal of Hepatology
Manuscript ID 87599
Country India
Received
2023-08-17 18:15
Peer-Review Started
2023-08-17 18:17
To Make the First Decision
Return for Revision
2023-09-06 00:44
Revised
2023-09-14 18:26
Second Decision
2023-10-07 02:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-10-08 07:44
Articles in Press
2023-10-08 07:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
2023-09-28 05:25
Typeset the Manuscript
2023-10-09 02:37
Publish the Manuscript Online
2023-10-24 08:39
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Prevalence and risk factors of lymphatic dysfunction in cirrhosis patients with refractory ascites: An often unconsidered mechanism
Manuscript Source Invited Manuscript
All Author List Rahul Arya, Ramesh Kumar, Tarun Kumar, Sudhir Kumar, Utpal Anand, Rajeev Nayan Priyadarshi and Tanmoy Maji
ORCID
Author(s) ORCID Number
Rahul Arya http://orcid.org/0000-0003-3714-0990
Tarun Kumar http://orcid.org/0000-0001-5554-3975
Sudhir Kumar http://orcid.org/0000-0001-7117-1382
Utpal Anand http://orcid.org/0000-0003-0653-4129
Rajeev Nayan Priyadarshi http://orcid.org/0000-0003-2890-8910
Tanmoy Maji http://orcid.org/0000-0002-5115-3563
Funding Agency and Grant Number
Corresponding Author Ramesh Kumar, MD, Additional Professor, Department of Gastroenterology, All India Institute of Medical Sciences, Phulwari Sharif, Patna 801507, Bihar, India. docrameshkr@gmail.com
Key Words Cirrhosis; Lymphedema; Lymphangicetasia; Refractory ascites; Chylous ascites; Lymphocytopenia
Core Tip Lymphatic dysfunction is often underappreciated in advanced cirrhosis patients. Our study evaluated the magnitude, spectrum, and associations of lymphatic dysfunction in cirrhosis patients with refractory ascites (RA). Nearly half (44.5%) of the studied population (n = 155) revealed evidence of overt lymphatic dysfunction in the forms of peripheral lymphedema (33.5%), intestinal lymphangiectasia (27.0%), and chylous ascites (1.9%). Obesity, hypoproteinemia, and lymphocytopenia were independently associated with lymphatic dysfunction in said patients. From a therapeutic standpoint, it can be extremely important to evaluate lymphatic dysfunction in cirrhosis patients with RA since it would call for using different strategies for fluid mobilization.
Publish Date 2023-10-24 08:39
Citation Arya R, Kumar R, Kumar T, Kumar S, Anand U, Priyadarshi RN, Maji T. Prevalence and risk factors of lymphatic dysfunction in cirrhosis patients with refractory ascites: An often unconsidered mechanism. World J Hepatol 2023; 15(10): 1140-1152
URL https://www.wjgnet.com/1948-5182/full/v15/i10/1140.htm
DOI https://dx.doi.org/10.4254/wjh.v15.i10.1140
Full Article (PDF) WJH-15-1140-with-cover.pdf
Full Article (Word) WJH-15-1140.docx
STROBE Statement 87599-STROBE statement.pdf
Manuscript File 87599_Auto_Edited-CL-Filipodia-JLW.docx
Answering Reviewers 87599-Answering reviewers.pdf
Audio Core Tip 87599-Audio core tip.mp3
Biostatistics Review Certificate 87599-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 87599-Conflict-of-interest statement.pdf
Copyright License Agreement 87599-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 87599-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 87599-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 87599-Language certificate.pdf
Supplementary Material 87599-Supplementary material.pdf
Peer-review Report 87599-Peer-review(s).pdf
Scientific Misconduct Check 87599-Bing-Lin C-2.png
Scientific Editor Work List 87599-Scientific editor work list.pdf