| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Crohn's disease as the intestinal manifestation of pan-lymphatic dysfunction: An exploratory proposal based on basic and clinical data
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu-Wei Zhou, Yue Ren, Miao-Miao Lu, Ling-Ling Xu, Wei-Xin Cheng, Meng-Meng Zhang, Lin-Ping Ding, Dong Chen, Jian-Guo Gao, Juan Du, Ci-Liang Jin, Chun-Xiao Chen, Yun-Fei Li, Tao Cheng, Peng-Lei Jiang, Yi-Da Yang, Peng-Xu Qian, Peng-Fei Xu and Xi Jin |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Xi Jin, MD, PhD, Chief Physician, Department of Gastroenterology, The First Affiliated Hospital of Zhejiang University School of Medicine, No. 79 Qingchun Road, Shangcheng District, Hangzhou 310003, Zhejiang Province, China. jxfl007@zju.edu.cn |
| Key Words |
Inflammatory bowel disease; Crohn’s disease; Lymphatic system; Inside-out model; Immune cells; Zebrafish |
| Core Tip |
The lymphatic system plays an active role in the pathogenesis, progression, and complications of certain diseases. Our review proposes an innovative concept of pan-lymphatic dysfunction and suggests Crohn’s disease (CD) as the intestinal manifestation of pan-lymphatic dysfunction using basic and clinical preliminary data, which may bring new perspectives to both the scientific study and clinical management of CD. |
| Publish Date |
2024-01-06 12:15 |
| Citation |
Zhou YW, Ren Y, Lu MM, Xu LL, Cheng WX, Zhang MM, Ding LP, Chen D, Gao JG, Du J, Jin CL, Chen CX, Li YF, Cheng T, Jiang PL, Yang YD, Qian PX, Xu PF, Jin X. Crohn’s disease as the intestinal manifestation of pan-lymphatic dysfunction: An exploratory proposal based on basic and clinical data. World J Gastroenterol 2024; 30(1): 34-49 |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i1/34.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i1.34 |
