Publication Name	World Journal of Experimental Medicine
Manuscript ID	88674
Country	Egypt

Received	2023-10-04 14:25
Peer-Review Started	2023-10-04 14:27
To Make the First Decision
Return for Revision	2023-12-06 09:26
Revised	2023-12-16 15:31
Second Decision	2024-01-04 02:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-01-04 07:46
Articles in Press	2024-01-04 07:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-02-06 09:36
Publish the Manuscript Online	2024-03-19 14:54

ISSN	2220-315x (online)
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Category	Infectious Diseases
Manuscript Type	Field of Vision
Article Title	COVID-19 mortality paradox (United States vs Africa): Mass vaccination vs early treatment
Manuscript Source	Invited Manuscript
All Author List	Mina Thabet Kelleni
ORCID	Author(s) ORCID Number Mina Thabet Kelleni http://orcid.org/0000-0001-6290-6025
Funding Agency and Grant Number
Corresponding Author	Mina Thabet Kelleni, MD, PhD, Assistant Professor, Pharmacology Department, College of Medicine, Minia University, Main Road Shalaby Land, PO Box 61519, Minya 61111, Egypt. mina.kelleni@mu.edu.eg
Key Words	COVID-19; Early treatment; Kelleni’s Protocol; Mandates; Mortality Paradox; SARS-CoV-2 Nucleic acid based vaccines
Core Tip	Coronavirus disease 2019 (COVID-19) has claimed the lives of millions of people worldwide. Paradoxically, the highest mortality numbers were encountered in countries that adopted the Western approach of mass nucleic acid based vaccination and rapidly approved drugs such as remdesivir, molnupiravir and nirmatrelvir-ritonavir (Paxlovid). In contrast, most developing countries that adopted early treatment using uniquely repurposed safe immune-modulatory drugs, as best scientifically documented in Kelleni’s protocol, experienced the lowest COVID-19 mortality rates. In this field of vision perspective, I aim to explain the COVID-19 mortality paradox by demonstrating our African scientific approach which rejected compulsory vaccination with nucleic acid based vaccines as well as many other Western mandates. Early treatment using Kelleni’s protocol has saved the lives of geriatric, immune-compromised and other comorbid COVID-19 patients, while young and otherwise healthy patients lost their lives in developed countries like the United States.
Publish Date	2024-03-19 14:54
Citation	Kelleni MT. COVID-19 mortality paradox (United States vs Africa): Mass vaccination vs early treatment. World J Exp Med 2024; 14(1): 88674
URL	https://www.wjgnet.com/2220-315x/full/v14/i1/88674.htm
DOI	https://dx.doi.org/10.5493/wjem.v14.i1.88674

Full Article (PDF)	WJEM-14-88674-with-cover.pdf
Manuscript File	88674_Auto_Edited-LJH-YJP.docx
Answering Reviewers	88674-Answering reviewers.pdf
Audio Core Tip	88674-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	88674-Conflict-of-interest statement.pdf
Copyright License Agreement	88674-Copyright license agreement.pdf
Peer-review Report	88674-Peer-review(s).pdf
Scientific Misconduct Check	88674-Bing-Liu JH-2.png
Scientific Misconduct Check	88674-CrossCheck.png
Scientific Editor Work List	88674-Scientific editor work list.pdf