Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	88963
Country	China

Received	2023-10-16 14:46
Peer-Review Started	2023-10-16 14:48
To Make the First Decision
Return for Revision	2023-12-06 05:49
Revised	2023-12-06 12:16
Second Decision	2024-01-08 03:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-01-08 07:56
Articles in Press	2024-01-08 07:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-01-29 00:26
Publish the Manuscript Online	2024-02-02 09:42

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Observational Study
Article Title	Prognostic value of circulating tumor cells combined with neutrophil-lymphocyte ratio in patients with hepatocellular carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Jia-Li Chen, Lu Guo, Zhen-Ying Wu, Kun He, Han Li, Chi Yang and Yun-Wei Han
ORCID	Author(s) ORCID Number Jia-Li Chen http://orcid.org/0000-0002-2692-8179 Lu Guo http://orcid.org/0000-0002-0938-9695 Zhen-Ying Wu http://orcid.org/0000-0002-2269-8804 Kun He http://orcid.org/0000-0002-1510-860X Han Li http://orcid.org/0000-0003-0846-3846 Chi Yang http://orcid.org/0009-0007-6370-5541 Yun-Wei Han http://orcid.org/0000-0002-0942-9095
Funding Agency and Grant Number
Corresponding Author	Yun-Wei Han, MD, PhD, Professor, Researcher, Department of Oncology, The Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Jiangyang District, Luzhou 646000, Sichuan Province, China. lanpaoxiansheng@126.com
Key Words	Circulating tumor cells; Neutrophil–lymphocyte ratio; Hepatocellular carcinoma; Prognosis; Survival; Marker
Core Tip	This study evaluates whether the combination of programmed death-ligand 1 on circulating tumor cells (CTCs) and the neutrophil-lymphocyte ratio can serve as a biomarker for predicting the prognosis of immune combination targeted therapy in hepatocellular carcinoma. Our study suggests the combination of CTC and neutrophil-to-lymphocyte ratio (NLR) scores as a new index for predicting survival in patients with hepatocellular carcinoma (HCC). HCC patients may benefit from pre-treatment assessment of their CTC-NLR scores for risk classification and clinical decision-making.
Publish Date	2024-02-02 09:42
Citation	Chen JL, Guo L, Wu ZY, He K, Li H, Yang C, Han YW. Prognostic value of circulating tumor cells combined with neutrophil-lymphocyte ratio in patients with hepatocellular carcinoma. World J Gastrointest Oncol 2024; 16(2): 372-385
URL	https://www.wjgnet.com/1948-5204/full/v16/i2/372.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i2.372

Full Article (PDF)	WJGO-16-372-with-cover.pdf
Full Article (Word)	WJGO-16-372.docx
STROBE Statement	88963-STROBE statement.pdf
Manuscript File	88963_Auto_Edited-JLW.docx
Answering Reviewers	88963-Answering reviewers.pdf
Audio Core Tip	88963-Audio core tip.mp3
Biostatistics Review Certificate	88963-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	88963-Conflict-of-interest statement.pdf
Copyright License Agreement	88963-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	88963-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	88963-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	88963-Language certificate.pdf
Peer-review Report	88963-Peer-review(s).pdf
Scientific Misconduct Check	88963-Bing-Lin C-2.png
Scientific Editor Work List	88963-Scientific editor work list.pdf