| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Preliminary exploration of animal models of congenital choledochal cysts
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shu-Hao Zhang, Yue-Bin Zhang, Duo-Te Cai, Tao Pan, Ken Chen, Yi Jin, Wen-Juan Luo, Zong-Wei Huang, Qing-Jiang Chen and Zhi-Gang Gao |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Key R&D Program of Zhejiang |
No. 2023C03029 |
| Health Science and Technology Plan of Zhejiang Province |
No. 2022RC201 |
| Zhejiang Provincial Natural Science Foundation Project |
No. LY20H030007 |
|
| Corresponding Author |
Zhi-Gang Gao, PhD, Chief Doctor, Department of General Surgery, Children's Hospital, Zhejiang University School of Medicine, No. 3333 Binsheng Road, Binjiang District, Hangzhou 310000, Zhejiang Province, China. ebwk@zju.edu.cn |
| Key Words |
Choledochal cyst; Animal model; Partial ligation; Cystic and fusiform dilation; Juvenile rats |
| Core Tip |
Recent studies have focused more on clinical issues rather than etiology and pathogenesis of choledochal cyst (CC). In this study, our partial ligation of the bile duct of juvenile rats successfully simulated the pathological processes of recanalization after incomplete obstruction of the distal bile duct. The postoperative disease progression of this model was more consistent with the natural course of CC formation which may assist in further basic research on the pathogenesis of CC. |
| Publish Date |
2024-03-14 17:31 |
| Citation |
Zhang SH, Zhang YB, Cai DT, Pan T, Chen K, Jin Y, Luo WJ, Huang ZW, Chen QJ, Gao ZG. Preliminary exploration of animal models of congenital choledochal cysts. World J Gastroenterol 2024; 30(10): 1420-1430 |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i10/1420.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i10.1420 |
