| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Observational Study |
| Article Title |
Systemic inflammation response index and weight loss as prognostic factors in metastatic pancreatic cancer: A concept study from the PANTHEIA-SEOM trial
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Vilma Pacheco-Barcia, Sara Custodio-Cabello, Fatima Carrasco-Valero, Magda Palka-Kotlowska, Axel Mariño-Mendez, Alberto Carmona-Bayonas, Javier Gallego, A J Muñoz Martín, Paula Jimenez-Fonseca and Luis Cabezon-Gutierrez |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Vilma Pacheco-Barcia, MD, MSc, PhD, Doctor, Doctor, Department of Medical Oncology, Hospital Universitario de Torrejon, C/Mateo Inurria S/N, Madrid 28850, Spain. vepacheco@torrejonsalud.com |
| Key Words |
Pancreatic cancer; Nutrition; Prognostic factor; Inflammation; Advanced cancer; Systemic inflammatory response index; Weight loss |
| Core Tip |
Advancements in the therapeutic landscape for pancreatic cancer have been modest in the recent years and the prognostic potential of the systemic inflammation response index (SIRI) in advanced pancreatic cancer has garnered interest. Originating from the PANTHEIA-Spanish Society of Medical Oncology (SEOM) initiative, a multicentric, observational, study promoted by the SEOM Real World-Evidence work group, our pilot research seeks to bridge this knowledge gap. Specifically, we focused on the interplay between weight loss and the inflammatory state as demarcated by SIRI. A significant correlation between elevated SIRI levels and decreased survival in patients with metastatic pancreatic cancer, with a notable association with weight loss, was observed. |
| Publish Date |
2024-02-02 09:42 |
| Citation |
Pacheco-Barcia V, Custodio-Cabello S, Carrasco-Valero F, Palka-Kotlowska M, Mariño-Mendez A, Carmona-Bayonas A, Gallego J, Martín AJM, Jimenez-Fonseca P, Cabezon-Gutierrez L. Systemic inflammation response index and weight loss as prognostic factors in metastatic pancreatic cancer: A concept study from the PANTHEIA-SEOM trial. World J Gastrointest Oncol 2024; 16(2): 386-397 |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i2/386.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i2.386 |
