Publication Name	World Journal of Orthopedics
Manuscript ID	89263
Country	China

Received	2023-10-26 01:14
Peer-Review Started	2023-10-26 01:14
To Make the First Decision
Return for Revision	2023-12-12 07:41
Revised	2023-12-29 04:09
Second Decision	2024-01-16 02:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-01-16 07:26
Articles in Press	2024-01-16 07:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-02-02 01:38
Publish the Manuscript Online	2024-02-07 02:35

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Letter to the Editor
Article Title	Adenylate cyclase activates the cAMP signalling pathway to enhance platelet-rich plasma-treated Achilles tendon disease, a theoretical bioinformatics-based study
Manuscript Source	Unsolicited Manuscript
All Author List	Jing-Yi Sun, Cai Li and Feng-Ying Du
ORCID	Author(s) ORCID Number Jing-Yi Sun http://orcid.org/‪0009-0004-8221-0622‬ Feng-Ying Du http://orcid.org/0000-0002-2767-1301
Funding Agency and Grant Number
Corresponding Author	Feng-Ying Du, MD, Doctor, Department of Gastroenterological Surgery, Shandong Provincial Hospital of Shandong First Medical University, No. 324 Jingwu Road , Jinan 250021, Shandong Province, China. sdudfy@126.com
Key Words	Platelet-rich plasma; Achilles tendon disease; cAMP; Adenylate cyclase; Complementary target
Core Tip	The cAMP signalling pathway may be the key to enhancing the effectiveness of platelet-rich plasma (PRP) in the treatment of Achilles tendon disease. ADCY1-9 may be the key to activating the cAMP signalling network and is expected to be a complementary target for enhancing the effectiveness of PRP in the treatment of Achilles tendon disease.
Publish Date	2024-02-07 02:35
Citation	Sun JY, Li C, Du FY. Adenylate cyclase activates the cAMP signalling pathway to enhance platelet-rich plasma-treated Achilles tendon disease, a theoretical bioinformatics-based study. World J Orthop 2024; 15(2): 192-200
URL	https://www.wjgnet.com/2218-5836/full/v15/i2/192.htm
DOI	https://dx.doi.org/10.5312/wjo.v15.i2.192

Full Article (PDF)	WJO-15-192-with-cover.pdf
Full Article (Word)	WJO-15-192.docx
Manuscript File	89263_Auto_Edited-LJH-YJP.docx
Answering Reviewers	89263-Answering reviewers.pdf
Audio Core Tip	89263-Audio core tip.wav
Conflict-of-Interest Disclosure Form	89263-Conflict-of-interest statement.pdf
Copyright License Agreement	89263-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	89263-Language certificate.pdf
Peer-review Report	89263-Peer-review(s).pdf
Scientific Misconduct Check	89263-Bing-Liu JH-2.png
Scientific Misconduct Check	89263-CrossCheck.png
Scientific Editor Work List	89263-Scientific editor work list.pdf