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Articles Published Processes
3/22/2024 11:13:53 AM | Browse: 193 | Download: 787
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Received |
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2023-11-09 05:03 |
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Peer-Review Started |
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2023-11-09 05:05 |
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First Decision by Editorial Office Director |
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2023-12-08 02:36 |
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Return for Revision |
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2023-12-08 02:36 |
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Revised |
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2024-01-03 07:07 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-02-03 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-02-03 05:01 |
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Articles in Press |
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2024-02-03 05:01 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-03-13 07:05 |
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Publish the Manuscript Online |
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2024-03-22 11:13 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Etanercept-synthesizing adipose-derived stem cell secretome: A promising therapeutic option for inflammatory bowel disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Say-June Kim, Ok-Hee Kim, Ha-Eun Hong, Ji Hyeon Ju and Do Sang Lee |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) |
NRF-2021R1F1A1064566 |
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| Corresponding Author |
Do Sang Lee, MD, PhD, Doctor, Doctor, Professor, Department of Surgery, Seoul St. Mary’s Hospital, College of Medicine, the Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul 06591, South Korea. dosangs@catholic.ac.kr |
| Key Words |
Adipose-derived stem cells; Etanercept; Inflammatory bowel disease; Secretome; Tumor necrosis factor-α |
| Core Tip |
This study explores a promising therapeutic strategy for treating inflammatory bowel disease (IBD) by harnessing the potential of a secretome derived from adipose-derived stem cells (ASCs) engineered to produce etanercept, a tumor necrosis factor-blocking drug. The findings demonstrate that the Etanercept-Secretome (Et-Sec) offers enhanced anti-inflammatory effects compared to traditional etanercept treatment. This superior therapeutic potential of the Et-Sec in IBD is attributed to its unique combination of etanercept synthesis and the intrinsic anti-inflammatory and immunomodulatory properties of ASC secretome, making it a promising candidate for advanced IBD therapy. |
| Publish Date |
2024-03-22 11:13 |
| Citation |
Kim SJ, Kim OH, Hong HE, Ju JH, Lee DS. Etanercept-synthesizing adipose-derived stem cell secretome: A promising therapeutic option for inflammatory bowel disease. World J Gastrointest Surg 2024; In press |
| URL |
https://www.wjgnet.com/1948-9366/full/v16/i3/882.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v16.i3.882 |
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