Publication Name	World Journal of Hepatology
Manuscript ID	89707
Country	China

Received	2023-11-12 14:58
Peer-Review Started	2023-11-12 14:59
To Make the First Decision
Return for Revision	2023-12-10 07:23
Revised	2024-01-03 20:51
Second Decision	2024-02-06 02:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-02-06 06:21
Articles in Press	2024-02-06 06:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-13 03:16
Publish the Manuscript Online	2024-03-27 13:28

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Prognostic value of neutrophil-to-lymphocyte ratio in end-stage liver disease: A meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Xiang-Hao Cai, Yun-Ming Tang, Shu-Ru Chen, Jia-Hui Pang, Yu-Tian Chong, Hong Cao and Xin-Hua Li
ORCID	Author(s) ORCID Number Shu-Ru Chen http://orcid.org/0000-0002-8433-9866 Yu-Tian Chong http://orcid.org/0000-0001-8215-4393 Hong Cao http://orcid.org/0009-0006-4252-8278 Xin-Hua Li http://orcid.org/0000-0002-6748-9803
Funding Agency and Grant Number	Funding Agency Grant Number the Science and Technology Planning Project of Guangdong Province, China No. 2019B020228001 5010 Project of Sun Yat-sen University No. 2018024 Science and Technology Program of Guangzhou, China No. 202103000060
Corresponding Author	Xin-Hua Li, MD, PhD, Doctor, Department of Infectious Disease, Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Tianhe District, Guangzhou 510630, Guangdong Province, China. lixinh8@mail.sysu.edu.cn
Key Words	Neutrophil-to-lymphocyte ratio; End stage liver diseases; Prognosis; Meta-analysis; Mortality
Core Tip	This meta-analysis examines the association between neutrophil-to-lymphocyte ratio (NLR) and mortality in patients with end-stage liver disease (ESLD). It finds that elevated NLR is correlated with higher risk of death. Specifically, NLR levels were higher in non-survivors than survivors, and high NLR predicted increased mortality risk as indicated by univariate and multivariate hazards ratios and odds ratios. Moreover, NLR had stronger prognostic value in Asian populations, suggesting it may be a useful biomarker for identifying high-risk ESLD patients, particularly in Asia.
Publish Date	2024-03-27 13:28
Citation	Cai XH, Tang YM, Chen SR, Pang JH, Chong YT, Cao H, Li XH. Prognostic value of neutrophil-to-lymphocyte ratio in end-stage liver disease: A meta-analysis. World J Hepatol 2024; 16 (3): 477-489
URL	https://www.wjgnet.com/1948-5182/full/v16/i3/477.htm
DOI	https://dx.doi.org/10.4254/wjh.v16.i3.477

Full Article (PDF)	WJH-16-477-with-cover.pdf
PRISMA 2009 Checklist	89707-PRISMA 2009 Checklist.pdf
Manuscript File	89707_Auto_Edited-LJH-YJP.docx
Answering Reviewers	89707-Answering reviewers.pdf
Audio Core Tip	89707-Audio core tip.mp3
Biostatistics Review Certificate	89707-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	89707-Conflict-of-interest statement.pdf
Copyright License Agreement	89707-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	89707-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	89707-Language certificate.pdf
Supplementary Material	89707-Supplementary material.pdf
Peer-review Report	89707-Peer-review(s).pdf
Scientific Misconduct Check	89707-Bing-Liu JH-2.png
Scientific Misconduct Check	89707-CrossCheck.png
Scientific Editor Work List	89707-Scientific editor work list.pdf