Publication Name	World Journal of Orthopedics
Manuscript ID	89734
Country	United Kingdom

Received	2023-11-10 23:10
Peer-Review Started	2023-11-10 23:12
To Make the First Decision
Return for Revision	2024-01-12 08:59
Revised	2024-02-07 20:33
Second Decision	2024-03-19 02:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-03-19 09:32
Articles in Press	2024-03-19 09:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-10 01:15
Publish the Manuscript Online	2024-04-16 08:04

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Observational Study
Article Title	Safety of tranexamic acid in surgically treated isolated spine trauma
Manuscript Source	Unsolicited Manuscript
All Author List	Wajiha Zahra, Sandeep Krishan Nayar, Ashwin Bhadresha, Vinay Jasani and Syed Aftab
ORCID	Author(s) ORCID Number Wajiha Zahra http://orcid.org/0000-0002-9813-0414
Funding Agency and Grant Number
Corresponding Author	Wajiha Zahra, MBBS, MSc, Doctor, Trauma and Orthopedics Department, University Hospital of North Midlands NHS Trust, Newcastle Road, Stoke-on-Trent ST4 6QG, United Kingdom. wajiha.zahra@nhs.net
Key Words	Tranexamic acid; Infection; Trauma; Thromboembolic disease; Minimally invasive; Percutaneous
Core Tip	Since the introduction of tranexamic acid (TXA), it has been used for reducing blood loss in various surgical specialties such as Urology, general surgery, trauma and orthopedics. TXA use for elective spine surgery is well documented but there is scarce literature to explain the safety of TXA in isolated whole spine trauma. This study looks at the clinical practice of spine surgeons in two major United Kingdom trauma centres and explore the safety of TXA. The study sets the foundation for future research with larger number of patients and to improve the clinical practice.
Publish Date	2024-04-16 08:04
Citation	Zahra W, Nayar SK, Bhadresha A, Jasani V, Aftab S. Safety of tranexamic acid in surgically treated isolated spine trauma. World J Orthop 2024; 15(4): 346-354
URL	https://www.wjgnet.com/2218-5836/full/v15/i4/346.htm
DOI	https://dx.doi.org/10.5312/wjo.v15.i4.346

Full Article (PDF)	WJO-15-346-with-cover.pdf
STROBE Statement	89734-STROBE statement.pdf
Manuscript File	89734_Auto_Edited-YJP.docx
Answering Reviewers	89734-Answering reviewers.pdf
Audio Core Tip	89734-Audio core tip.mp4
Biostatistics Review Certificate	89734-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	89734-Conflict-of-interest statement.pdf
Copyright License Agreement	89734-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	89734-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	89734-Institutional review board statement.pdf
Peer-review Report	89734-Peer-review(s).pdf
Scientific Editor Work List	89734-Scientific editor work list.pdf