Publication Name	World Journal of Stem Cells
Manuscript ID	89874
Country	Italy

Received	2023-11-15 08:35
Peer-Review Started	2023-11-15 08:36
To Make the First Decision
Return for Revision	2023-12-17 01:37
Revised	2023-12-18 11:07
Second Decision	2023-12-28 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-12-28 05:46
Articles in Press	2023-12-28 05:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-01-16 13:10
Publish the Manuscript Online	2024-01-22 04:25

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Biology
Manuscript Type	Editorial
Article Title	Use of priming strategies to advance the clinical application of mesenchymal stromal/stem cell-based therapy
Manuscript Source	Invited Manuscript
All Author List	Vitale Miceli
ORCID	Author(s) ORCID Number Vitale Miceli http://orcid.org/0000-0001-8922-9909
Funding Agency and Grant Number
Corresponding Author	Vitale Miceli, PhD, Academic Editor, Research Scientist, Department of Research, Istituto Mediterraneo per i Trapianti e Terapie ad alta Specializzazione, Via Tricomi 5, Palermo 90127, Italy. vmiceli@ismett.edu
Key Words	Mesenchymal stromal/stem cells; Therapeutic properties; Paracrine effects; Cell priming; Cell-free therapies; Regenerative medicine
Core Tip	Mesenchymal stromal/stem cells (MSCs) offer important therapeutic effects in the field of regenerative medicine. Their key role lies in the production of paracrine factors that modulate tissue environments and allow their repair following insults. Recently, MSC-derived products such as exosomes and conditioned media are replacing whole MSCs in clinical applications. In this regard, to optimize the results of MSC-based treatment, researchers have explored priming strategies in order to enhance MSC properties. Realizing the full potential of MSC therapy depends on identifying the right tissue source and developing priming strategies specific to the disease being treated.
Publish Date	2024-01-22 04:25
Citation	Miceli V. Use of priming strategies to advance the clinical application of mesenchymal stromal/stem cell-based therapy. World J Stem Cells 2024; 16(1): 7-18
URL	https://www.wjgnet.com/1948-0210/full/v16/i1/7.htm
DOI	https://dx.doi.org/10.4252/wjsc.v16.i1.7

Full Article (PDF)	WJSC-16-7-with-cover.pdf
Full Article (Word)	WJSC-16-7.docx
Manuscript File	89874_Auto_Edited-YJP.docx
Answering Reviewers	89874-Answering reviewers.pdf
Audio Core Tip	89874-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	89874-Conflict-of-interest statement.pdf
Copyright License Agreement	89874-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	89874-Language certificate.pdf
Peer-review Report	89874-Peer-review(s).pdf
Scientific Misconduct Check	89874-Bing-Wang JJ-2.png
Scientific Editor Work List	89874-Scientific editor work list.pdf
CrossCheck Report	89874-CrossCheck report.pdf