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Articles Published Processes
3/14/2024 5:31:16 PM | Browse: 107 | Download: 332
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Received |
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2023-11-17 18:00 |
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Peer-Review Started |
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2023-11-17 18:02 |
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To Make the First Decision |
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Return for Revision |
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2023-12-14 01:24 |
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Revised |
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2023-12-25 07:58 |
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Second Decision |
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2024-01-24 02:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-01-24 05:57 |
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Articles in Press |
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2024-01-24 05:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-02-02 01:10 |
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Publish the Manuscript Online |
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2024-03-14 17:31 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Overview of the immunological mechanisms in hepatitis B virus reactivation: Implications for disease progression and management strategies
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hui Ma, Qing-Zhu Yan, Jing-Ru Ma, Dong-Fu Li and Jun-Ling Yang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Qing-Zhu Yan, MBBS, MD, Associate Professor, Department of Ultrasound Medicine, The Second Hospital of Jilin University, No. 218 Ziqiang Street, Nanguan District, Changchun 130000, Jilin Province, China. yanqingzhu@jlu.edu.cn |
| Key Words |
Hepatitis B virus reactivation; Immunological mechanisms; Disease progression; Management strategies; Immune response |
| Core Tip |
Hepatitis B virus (HBV) reactivation poses a substantial clinical challenge, demanding a nuanced understanding of immunological mechanisms for effective management. This comprehensive review navigates the intricate landscape of HBV reactivation, spotlighting the delicate balance between host immune responses and viral factors. Emphasis is placed on the roles of T cells, natural killer cells, and antigen-presenting cells in disease progression, alongside the repercussions on severity, hepatic flares, liver fibrosis, and hepatocellular carcinoma. Critical analysis of management strategies, spanning anti-viral and immunomodulatory approaches, informs evidence-based practices. Prophylactic anti-viral therapy’s role during immunosuppression and the potential of innovative immunotherapies are explored, contributing significantly to informed disease management and improved patient outcomes. |
| Publish Date |
2024-03-14 17:31 |
| Citation |
Ma H, Yan QZ, Ma JR, Li DF, Yang JL. Overview of the immunological mechanisms in hepatitis B virus reactivation: Implications for disease progression and management strategies. World J Gastroenterol 2024; 30(10): 1295-1312 |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i10/1295.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i10.1295 |
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