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Articles Published Processes
2/6/2024 6:16:03 AM | Browse: 164 | Download: 196
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Received |
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2023-11-23 12:04 |
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Peer-Review Started |
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2023-11-23 12:05 |
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To Make the First Decision |
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Return for Revision |
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2023-12-06 03:12 |
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Revised |
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2023-12-13 16:12 |
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Second Decision |
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2024-01-08 03:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2024-01-08 08:32 |
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Articles in Press |
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2024-01-08 08:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-02-01 13:27 |
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Publish the Manuscript Online |
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2024-02-06 06:16 |
ISSN |
2220-3206 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Neuroimaging |
Manuscript Type |
Retrospective Study |
Article Title |
Neuropathological characteristics of abnormal white matter functional signaling in adolescents with major depression
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Xin-Lin Huang, Ju Gao, Yong-Ming Wang, Feng Zhu, Jing Qin, Qian-Nan Yao, Xiao-Bin Zhang and Hong-Yan Sun |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
the Suzhou Clinical Medical Center for Mood Disorders |
Szlcyxzx202109 |
Jiangsu Provincial Department of Science and Technology for Social Development-General Project |
BE2022735 |
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Corresponding Author |
Hong-Yan Sun, MD, PhD, Chief Doctor, Department of Radiology, The Affiliated Guangji Hospital of Soochow University, No. 11 Guangqian Road, Suzhou 215137, Jiangsu Province, China. hoya12@126.com |
Key Words |
White matter; Regional homogeneity; The fractional amplitude of low-frequency fluctuations; Independent component analysis; Adolescents; Major depression disorders |
Core Tip |
This groundbreaking study investigates white matter (WM) functional signals in adolescents with major depressive disorder (MDD), an area often overlooked in research. Utilizing advanced imaging techniques, the study identifies specific abnormalities in WM signals, revealing decreased fractional amplitude of low frequency fluctuations in key regions and altered regional homogeneity and independent component analysis patterns. Notably, these changes correlate with suicidality scales, indicating a potential link between WM anomalies and severity of depression. The study pioneers a crucial shift in understanding MDD's neuropathogenesis, offering novel insights and support for future research and predictive measures. |
Publish Date |
2024-02-06 06:16 |
Citation |
Huang XL, Gao J, Wang YM, Zhu F, Qin J, Yao QN, Zhang XB, Sun HY. Neuropathological characteristics of abnormal white matter functional signaling in adolescents with major depression. World J Psychiatry 2024; 14(2): 276-286 |
URL |
https://www.wjgnet.com/2220-3206/full/v14/i2/276.htm |
DOI |
https://dx.doi.org/10.5498/wjp.v14.i2.276 |
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