Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	90602
Country	China

Received	2023-12-08 06:30
Peer-Review Started	2023-12-08 06:30
To Make the First Decision
Return for Revision	2023-12-22 05:15
Revised	2024-01-08 09:11
Second Decision	2024-02-07 03:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-02-07 06:35
Articles in Press	2024-02-07 06:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-27 07:10
Publish the Manuscript Online	2024-04-11 02:23

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Long noncoding RNAs HAND2-AS1 ultrasound microbubbles suppress hepatocellular carcinoma progression by regulating the miR-873-5p/tissue inhibitor of matrix metalloproteinase-2 axis
Manuscript Source	Unsolicited Manuscript
All Author List	Qiang Zou, Hao-Wen Wang, Xi-Liang Di, Yuan Li and Hui Gao
ORCID	Author(s) ORCID Number Hui Gao http://orcid.org/0009-0003-3172-866X
Funding Agency and Grant Number
Corresponding Author	Hui Gao, N/A, N/A, Department of Comprehensive Oncology, Baotou Cancer Hospital, No. 18 Tuanjie Street, Baotou 014030, Inner Mongolia Autonomous Region, China. gaohui145@163.com
Key Words	Hepatocellular carcinoma; Ultrasound microbubbles; Long noncoding RNA HAND2-AS1; miR-873-5p; Tissue inhibitor of matrix metalloproteinase-2
Core Tip	In this study, we found that ultrasound microbubbles loaded with long noncoding RNA HAND2-AS1 inhibited the growth of hepatocellular carcinoma cells and tumor formation in mice in vivo and in vitro by downregulating miR-873-5p to promote tissue inhibitor of matrix metalloproteinase-2 expression.
Publish Date	2024-04-11 02:23
Citation	Zou Q, Wang HW, Di XL, Li Y, Gao H. Long noncoding RNAs HAND2-AS1 ultrasound microbubbles suppress hepatocellular carcinoma progression by regulating the miR-873-5p/tissue inhibitor of matrix metalloproteinase-2 axis. World J Gastrointest Oncol 2024; 16(4): 1547-1563
URL	https://www.wjgnet.com/1948-5204/full/v16/i4/1547.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i4.1547

Full Article (PDF)	WJGO-16-1547-with-cover.pdf
The ARRIVE Guidelines	90602-The ARRIVE guidelines.pdf
Manuscript File	90602_Auto_Edited-JLW.docx
Answering Reviewers	90602-Answering reviewers.pdf
Audio Core Tip	90602-Audio core tip.mp3
Biostatistics Review Certificate	90602-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	90602-Conflict-of-interest statement.pdf
Copyright License Agreement	90602-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	90602-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	90602-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	90602-Language certificate.pdf
Peer-review Report	90602-Peer-review(s).pdf
Scientific Misconduct Check	90602-Bing-Qu XL-2.jpg
Scientific Editor Work List	90602-Scientific editor work list.pdf