Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	90644
Country	China

Received	2023-12-10 01:21
Peer-Review Started	2023-12-10 01:21
To Make the First Decision
Return for Revision	2023-12-18 08:57
Revised	2023-12-26 14:28
Second Decision	2024-01-30 02:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-01-30 07:05
Articles in Press	2024-01-30 07:05
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-02-03 03:53
Typeset the Manuscript	2024-02-19 09:01
Publish the Manuscript Online	2024-02-25 15:12

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Mutational landscape of TP53 and CDH1 in gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Hong-Qiao Cai, Li-Yue Zhang, Li-Ming Fu, Bin Xu and Yan Jiao
ORCID	Author(s) ORCID Number Yan Jiao http://orcid.org/0000-0001-6914-7949
Funding Agency and Grant Number	Funding Agency Grant Number Youth Development Fund Task Book of the First Hospital of Jilin University JDYY13202210
Corresponding Author	Yan Jiao, MD, PhD, Adjunct Associate Professor, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin Province, China. lagelangri1@126.com
Key Words	TP53; CDH1; Gastric cancer; Gene mutation; Methylation
Core Tip	The separation of TP53 and CDH1 mutations in gastric cancer (GC) demonstrates their separate processes. Mutations in TP53 are linked to advanced-stage cancers and poor prognoses, whereas CDH1 mutations are linked to widespread GC. This work emphasizes the variability of GC and sheds light on prospective targeted therapeutics based on distinct mutation patterns. Understanding the mutational landscape of TP53 and CDH1 can help to develop tailored therapy strategies for GC patients.
Publish Date	2024-02-25 15:12
Citation	Cai HQ, Zhang LY, Fu LM, Xu B, Jiao Y. Mutational landscape of TP53 and CDH1 in gastric cancer. World J Gastrointest Surg 2024; 16(2): 276-283
URL	https://www.wjgnet.com/1948-9366/full/v16/i2/276.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i2.276

Full Article (PDF)	WJGS-16-276-with-cover.pdf
Full Article (Word)	WJGS-16-276.docx
Manuscript File	90644-Review-FilipodiaCL.docx
Answering Reviewers	90644-Answering reviewers.pdf
Audio Core Tip	90644-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	90644-Conflict-of-interest statement.pdf
Copyright License Agreement	90644-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	90644-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	90644-Language certificate.pdf
Peer-review Report	90644-Peer-review(s).pdf
Scientific Misconduct Check	90644-Bing-Wang JJ-2.png
Scientific Editor Work List	90644-Scientific editor work list.pdf