| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Research & Experimental Medicine |
| Manuscript Type |
Basic Study |
| Article Title |
Long-term effects of gestational diabetes mellitus on the pancreas of female mouse offspring
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Enriqueta Muñoz-Islas, Edgar David Santiago-SanMartin, Eduardo Mendoza-Sánchez, Héctor Fabián Torres-Rodríguez, Laura Yanneth Ramírez-Quintanilla, Christopher Michael Peters and Juan Miguel Jiménez-Andrade |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Council for Humanities, Science and Technology of Mexico CONAHCyT |
CB/2017-2018/A1-S-27869 |
|
| Corresponding Author |
Juan Miguel Jiménez-Andrade, PhD, Professor, Unidad Académica Multidisciplinaria Reynosa-Aztlán, Universidad Autónoma de Tamaulipas, 16 Calle y Lago de Chapala, Col. Aztlán, Reynosa 88740, Tamaulipas, Mexico. jandrade@docentes.uat.edu.mx |
| Key Words |
Gestational diabetes mellitus; Immunohistochemistry; Confocal microscopy; Pancreas; Offspring |
| Core Tip |
Gestational diabetes mellitus (GDM) predisposes offspring to develop metabolic disorders later in life, however, the underlying mechanisms are unknown. Here, using a well-established model of GDM, we report that while GDM did not modify body weight or blood glucose, it significantly increased the density of nerve axons, blood vessels, and macrophages in the pancreas of adult offspring born from dams with GDM. |
| Publish Date |
2024-04-12 01:04 |
| Citation |
Muñoz-Islas E, Santiago-SanMartin ED, Mendoza-Sánchez E, Torres-Rodríguez HF, Ramírez-Quintanilla LY, Peters CM, Jiménez-Andrade JM. Long-term effects of gestational diabetes mellitus on the pancreas of female mouse offspring. World J Diabetes 2024; 15(4): 758-768 |
| URL |
https://www.wjgnet.com/1948-9358/full/v15/i4/758.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v15.i4.758 |
